Pernio (Chilblains)
Chapter 51 Pernio (Chilblains) Jeffrey W. Olin, Amjad Al Mahameed Pernio, commonly known as chilblains, is a cold-induced localized inflammatory condition presenting as skin lesions predominantly on unprotected acral areas….
The Epidemiology of Peripheral Artery Disease
Chapter 16 The Epidemiology of Peripheral Artery Disease Michael H. Criqui Peripheral artery disease (PAD) is generally defined as partial or complete obstruction of one or more peripheral arteries due…
Vascular Embryology and Angiogenesis
Chapter 1 Vascular Embryology and Angiogenesis Daniel M. Greif In simple terms, the cardiovascular system consists of a sophisticated pump (i.e., the heart) and a remarkable array of tubes (i.e.,…
Surgical Treatment of Abdominal Aortic Aneurysms
Chapter 39 Surgical Treatment of Abdominal Aortic Aneurysms David H. Stone, Jack L. Cronenwett Abdominal aortic aneurysms (AAAs) remain a leading cause of death in the elderly. In the United…
Kawasaki Disease
Chapter 45 Kawasaki Disease David R. Fulton, Jane W. Newburger Kawasaki disease, initially described by Dr. Tomisaku Kawasaki in 1967,1 is an acute systemic vasculitis of uncertain etiology that predominantly…
Giant Cell Arteritis
Chapter 43 Giant Cell Arteritis Maria C. Cid, Peter A. Merkel Giant-cell (temporal) arteritis (GCA) is a chronic inflammatory arteritis that preferentially involves large and medium-sized arteries and affects persons…
The Endothelium
Chapter 2 The Endothelium Jane A. Leopold In 1839, the German physiologist Theodor Schwann became the first to describe a “thin, but distinctly perceptible membrane” that he observed as part…
Pathophysiology of Vasculitis
Chapter 9 Pathophysiology of Vasculitis Peter Libby The pathophysiological mechanisms that underlie vasculitis include elements of virtually all effector limbs of host defenses, including innate and adaptive immunity. Various classification…
Epidemiology and Pathophysiology of Mesenteric Vascular Disease
Chapter 26 Epidemiology and Pathophysiology of Mesenteric Vascular Disease Rachel C. Danczyk, Gregory J. Landry, Gregory L. Moneta Severe acute intestinal ischemia results from sudden symptomatic reduction in intestinal blood…
Pharmacology of Antithrombotic Drugs
Chapter 7 Pharmacology of Antithrombotic Drugs Omar P. Haqqani, Mark D. Iafrati, Jane E. Freedman Atherothrombotic disease and atherosclerotic plaque rupture is the leading cause of death worldwide. Its prevalence…
