Socioeconomic Aspects of Cardiovascular Health
Fig. 9.1 Kaplan–Meier survival curves comparing lower-income patients with higher-income patients by education categories. (a) Less educated group [log-rank test, P < 0.001; (b) More educated group [log-rank test, P…
Gene Polymorphisms and Signaling Defects
Gene SNP Variants Functional consequence References MTHFR 677C>T Homocysteine mediated Wilson et al. (2011), Johnson et al. (2011b) ACE rs4646994 Increased ACE activity Ned et al. (2012) AGT rs11206510 M235T…
Basic Principles of Molecular Pathophysiology and Etiology of Cardiovascular Disorders
Fig. 1.1 Schematic illustration of monogenetic and multifactorial cardiovascular diseases. In monogenetic diseases (left), genetic predisposition is responsible for disease onset induced by a relatively clear molecular pathway. Outcome and…
Stress and Psychological Factors
Behavioral mechanisms Pathophysiological mechanisms Unhealthy lifestyle (unhealthy diet,smoking, drinking more alcohol,being sedentary) Hypothalamic-pituitary-adrenal axis and autonomic nervous system dysfunction: increased sympathetic activity and/or reduced vagal activity, hypercortisolemia and elevated levels…
Quality of Life in Hypertensive Patients
Fig. 2.1 Quality of Life measured with the Psychological General Wellbeing Index in hypertensive (n = 1539) and normotensive subjects (n = 995) according to age. Reproduced from [15], with…
Quality of Life in Patients with Implantable Cardiac Devices
Study (year) NYHA class Number of patients Influence on HRQoL MUSTIC (2001) III 67 Significant improvement PATH-CHF I (2002) III-IV 42 Significant improvement PATH-CHF II (2003) II-IV 101 Significant improvement…
Quality of Life After Stroke
Fig. 8.1 Survival and health-related quality of life in post-stroke patients (100% represents the highest level of health-related quality of Life) HRQoL directly after stroke is low and is dependent…
Quality of Life in Patients with Coronary Artery Disease
Grade Description I Ordinary physical activity does not cause angina, such as walking and climbing stairs. Angina with strenuous or rapid or prolonged exertion at work or recreation. II Slight…