Chapter 7 Ion Channelopathies Mechanisms and Genotype-Phenotype Correlations Charles Antzelevitch, Jonathan M. Cordeiro Recent years have witnessed an explosion of knowledge contributing to the understanding of ion channelopathies associated with…
Chapter 9 Fundamentals of Regenerative Medicine and Its Applications to Electrophysiology David H. Lau, Michael R. Rosen The adult human heart has long been accepted as an end organ having…
Chapter 2 Principles of Cellular Architecture and Physiology with Applications in Electrophysiology Thomas J. Hund, Shane R. Cunha, Peter J. Mohler Specialized Excitable Cells Tightly Regulate Cardiac Depolarization The highly…
Chapter 6 Genomics and Principles of Clinical Genetics David J. Tester, Michael J. Ackerman The molecular millennium has provided researchers with the essential tools to identify the underlying genetic substrates…
Chapter 29 Electrophysiological Evaluation of Syncope Hugh Calkins Introduction This chapter reviews the role of electrophysiology (EP) testing and tilt-table (TT) testing in the evaluation of patients with syncope. A…
Chapter 11 Principles of Electropharmacology Penelope A. Boyden, David Eisner Long before actual medicines were available for arrhythmias, much had been written about the theoretical mechanisms of arrhythmias.1,2 Today, these…
Evaluation of SA Nodal Abnormalities Anatomy of the SA Node The SA node can be thought of as a subendocardial, comma-shaped structure, approximately 3 mm in width and 10 mm…
The Technology of Transcatheter Ablation Successful transcatheter ablation requires three things. First, a thorough understanding of the arrhythmia being treated—specifically, a precise understanding of the location and physiology of the…
General Classification of Supraventricular Tachyarrhythmias As described in Chapter 2, most supraventricular tachyarrhythmias are caused by either abnormal automaticity or reentry. Automatic Supraventricular Tachyarrhythmias Automatic supraventricular tachyarrhythmias are relatively uncommon,…
Ventricular Tachyarrhythmias and Sudden Death Sudden death (death that is instantaneous and completely unexpected) may well be the major public health problem in the United States today. If this statement…
