and Mark C. Mammel2, 3 (1) Division of Neonatal-Perinatal Medicine, C.S. Mott Children’s Hospital University of Michigan Health System, Ann Arbor, MI, USA (2) Neonatal Medicine, Children’s Hospitals and Clinics of Minnesota,…
and Mark C. Mammel2, 3 (1) Division of Neonatal-Perinatal Medicine, C.S. Mott Children’s Hospital University of Michigan Health System, Ann Arbor, MI, USA (2) Neonatal Medicine, Children’s Hospitals and Clinics of Minnesota,…
and Mark C. Mammel2, 3 (1) Division of Neonatal-Perinatal Medicine, C.S. Mott Children’s Hospital University of Michigan Health System, Ann Arbor, MI, USA (2) Neonatal Medicine, Children’s Hospitals and Clinics of Minnesota,…
and Mark C. Mammel2, 3 (1) Division of Neonatal-Perinatal Medicine, C.S. Mott Children’s Hospital University of Michigan Health System, Ann Arbor, MI, USA (2) Neonatal Medicine, Children’s Hospitals and Clinics of Minnesota,…
Fig. 6.1 Typical honeycomb lung. (a) High-resolution computed tomography (HRCT) shows clustered multiple cysts of which walls are relatively thick. The diameter of each cyst is one cm or less….
Fig. 7.1 Histology of UIP. (a) Panoramic view. Patchy involvement and perilobular dense fibrosis with structural remodeling. Bar: 1 cm. Hematoxylin-eosin staining (HE). (b, c) Fibroblastic focus on dense fibrosis (arrow)….
Fig. 15.1 A typical case of acute exacerbation after pulmonary resection for lung cancer. (a) A solid mass of adenocarcinoma in the middle lobe. (b) Basal slice of the CT…
MicroRNA Tumorigenesis IPF development Related molecules miR-21 ↑ ↑ TPM1, PDCD4, PTEN,TGFβ, NFIB, mapsin, Spry-2, MARCKS MMPs, RECK, SMAD2, SMAD7, FGF2 Let-7 ↓ ↓ TGFβ, HMGA2, SMAD3, RAS, CDC25A miR-155…
Treatment Recommended Strength of recommendation Quality of evidence Pharmacologic therapies Corticosteroid monotherapy No Strong ⊕○○○ Colchicine No Strong ⊕○○○ Cyclosporine A No Strong ⊕○○○ Corticosteroid + immunomodulatory No Strong ⊕○○○ Corticosteroid + azathioprine + acetylcysteine Majority…
Study Number of patients with CPFE/with IIPs Prevalence (%) Akira et al. [8] 15/80 18.8 Choi et al. [9] 66/254 26.0 Copley et al. [10] 76/212 35.8 Doherty et al….
