Measles Virus
Fig. 8.1 Ultrastructure of the measles virus showing a spherical, enveloped virion with a non-segmented negative-stranded RNA genome (With permission from Lancet [Reproduced with permission of Exp. Rev. Mol. Med…
SV40 and the Lung
Fig. 22.1 Electron photomicrograph showing cell infected with SV40 virus. Depicted is the nucleus of the cell packed with paracrystalline arrays of viruses, seen here as approximately 40 nm dark…
Human Papillomavirus-Related Pulmonary Neoplasia
Fig. 19.1 (a, b) Diagrammatic representation of HPV 1 showing capsids made up of a layer of nearly continuous density. (a) Surface view, (b) cross-sectional view (Adapted from Baker TS…
Human Metapneumovirus
Fig. 12.1 (a) hMPV infection. Note severe bronchiolitis with ulcerated bronchiolar epithelium. (b) Higher power showing accumulation of intra-alveolar macrophages. (c) Note pulmonary congestion and mild interstitial lymphocytic inflammation. (d)…
Varicella Zoster Virus
Fig. 7.1 Varicella virus. Round to hexagonal or “stop sign”-shaped, targetoid viral particles, cell culture media. Original magnification × 57000 (Courtesy of Dr. Richard Kradin and Dr. William Taylor, with…
Respiratory Syncytial Virus
Fig. 11.1 Panel A: Respiratory syncytial virus pneumonia. Note cuff-like intense bronchiolar and peribronchiolar inflammatory reaction. Hematoxylin and eosin. Panel B: Same bronchiole illustrated in Panel A showing RSV antigen….
Lung Defenses
Fig. 2.1 Antiviral action of interferon: Interferon (IFN) synthesis and release are often induced by a virus infection when cellular sensors recognize their pathogen-associated molecular patterns such as double-stranded RNA…
The Pathophysiology, Presentation and Diagnostic Investigation of Pulmonary Hypertension
Figure 1.1 Factors involved in the pathophysiology of pulmonary arterial hypertension Vasoconstriction In accordance with Poiseuille’s law the flow of blood through a vessel is proportional to its radius to…
Current Treatment Strategies, Guidelines and New Therapies
Figure 3.1 Survival plot before and after the advent of targeted vasodilator therapy, using REVEAL registry data (2012) of idiopathic and familial PAH matched to that from National Institutes of…
