© Springer International Publishing AG 2017Jon Kobashigawa (ed.)Clinical Guide to Heart Transplantation10.1007/978-3-319-43773-6_18 18. The Future of Heart Transplantation Jon Kobashigawa1, 2 (1) Director, Advanced Heart Disease Section, Cedars-Sinai Heart Institute, Los Angeles, CA, USA (2)…
ACCF/AHA stages of HF NYHA functional classification A At high risk for HF but without structural heart disease or symptoms of HF None B Structural heart disease but without signs…
Post-operative 12-lead ECG Invasive arterial pressure monitoring Right atrial or central venous pressure monitoring Left atrial or pulmonary artery wedge pressure monitoring Intermittent measures of cardiac output Arterial oxygen saturation…
Fig. 7.1 Biatrial compared to bicaval technique for cardiac transplantation (Reused with permission from Chen et al. [15]) Bicaval Technique Operative Technique Preparation of the recipient mediastinum is largely similar…
Fig. 6.1 CDC and flow methods for cross-matching and determination of circulating HLA alloantibodies Abbreviations: CDC Complement Dependent Cytotoxicity, AHG Anti-human Globulin (Reused with permission from Tinckam and Chandraker [29])…
Underlying medical conditions (see Chap. 3) Antibiotic/medication allergies, adverse reactions Chest radiograph (to look for infiltrates, granumolas, scarring) Dental assessment Social/sexual history; high-risk behaviors, intravenous drug use, sexually transmitted diseases…
Fig. 10.1 Diagram of mechanisms of action of common immunosuppressants in heart transplant. Through various pathways, the drugs inhibit T-cell proliferation. Abbreviations: G1 (first growth phase), S (synthesis of DNA),…
Fig. 5.1 The HLA gene cluster is localized on chromosome 6. HLA class I genes (HLA-A, B, C) encode HLA class I heavy chain which pairs with non-polymorphic protein β2-microglobulin…
Status 1A A patient listed as Status 1A is an admitted inpatient at the listing transplant center hospital or an affiliated VA hospital and has at least one of the…
Fig. 1.1 A cube of material is subject to force parallel to a face which cause shearing and forces normal to each face which cause compression 1.1 Solid Mechanics Solid mechanics…
