Age affects early mortality in TAVI




Background


TAVI was developed to treat elderly patients (pts) with symptomatic aortic valve stenosis considered at very high risk or with serious contraindication for aortic valve replacement. The aim of the study is to compare pts above and below 80 years of age according to 30-day VARC mortality.




Methods


Between May 2008 and May 2011, 95 consecutive pts underwent TAVI at our institution. Mean age was 81.9 ± 7.2. Sixty-one (64.2%) pts were > 80 years old (group 1) and 34 (35.8%) pts were ≤ 80 years old (group 2).




Methods


Between May 2008 and May 2011, 95 consecutive pts underwent TAVI at our institution. Mean age was 81.9 ± 7.2. Sixty-one (64.2%) pts were > 80 years old (group 1) and 34 (35.8%) pts were ≤ 80 years old (group 2).




Results


Group 1 and group 2 were different for sex, cirrhosis, cancer, and COPD ( Table 1 ). Logistic EuroSCORE (LES) and STS Predicted Risk of mortality (STS-PROM) were respectively: 21.4% ± 10.5% and 8.2% ± 5.4% in Group 1; 17.7% ± 12.5% and 9.1% ± 9.4% in Group 2. VARC mortality showed significant difference between group 1 and 2: 9.83% and 26.47% respectively ( P < .001). At the univariate analysis to be octogenarians seems to be protective for VARC mortality (RR 0.37, CI 0.14–0.95).



Table 1





































































> 80 yo mean ± SD n = 61 < 80 yo mean ± SD n = 34 P value
Age 86.1 ± 3.4 78.9 ± 12.0 <.001
Female 75.4% 41.2% .002
BMI 24.9 ± 3.8 26.3 ± 5.9 .17
Diabetes mellitus 31.1% 32.3% .31
IDDM 9.8% 17.6% .43
NYHA class 3.0 ± 0.7 3.1 ± 0.7 .41
Current coronaropathy 55.7% 44.1% .38
Atrial fibrillation 21.3% 29.4% .52
Cirrhosis 0% 14.7% .009
Cancer 8.2% 32.3% .006
COPD ≥II (STS definition) 8.2% 41.2% <.001
VGF ≥IV (KDOQI definition) 27.9% 32.3% .82

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Nov 16, 2017 | Posted by in CARDIOLOGY | Comments Off on Age affects early mortality in TAVI

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