Combined treatment of thrombotic coronary occlusions by thrombectomy and by intracoronary administration of abciximab via an intracoronary perfusion catheter—which treatment first?




Purpose


Thrombectomy and intracoronary administration of abciximab via an intracoronary perfusion catheter have been demonstrated to reduce thrombus burden. We analyzed two different treatment strategies: (1) first thrombus-aspiration to reduce thrombus size, then lysis of the rest-thrombus by locally administered abciximab via the ClearWay (CW) RX perfusion catheter versus (2) first pharmacological thrombus-reduction by locally administered abciximab, then, if necessary, thrombus-aspiration of the rest-thrombus.




Methods


This retrospective study included 68 patients who presented with an acute coronary syndrome due to an intracoronary thrombus between May 2009 and April 2011. Thrombus-aspiration first strategy was performed in 39 patients, abciximab first strategy in 29 patients. The primary endpoint was defined as final improvement in Thrombolysis In Myocardial Infarction (TIMI) flow.




Methods


This retrospective study included 68 patients who presented with an acute coronary syndrome due to an intracoronary thrombus between May 2009 and April 2011. Thrombus-aspiration first strategy was performed in 39 patients, abciximab first strategy in 29 patients. The primary endpoint was defined as final improvement in Thrombolysis In Myocardial Infarction (TIMI) flow.

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Nov 16, 2017 | Posted by in CARDIOLOGY | Comments Off on Combined treatment of thrombotic coronary occlusions by thrombectomy and by intracoronary administration of abciximab via an intracoronary perfusion catheter—which treatment first?

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