Thalassemia and iron overload cardiomyopathy: Pathophysiological insights, clinical implications, and management strategies

Apr 20, 2025 by in CARDIOLOGY Comments Off on Thalassemia and iron overload cardiomyopathy: Pathophysiological insights, clinical implications, and management strategies

Abstract Thalassemia is a hereditary blood disorder characterized by reduced hemoglobin production, leading to chronic anemia. A major complication of thalassemia is iron overload, primarily due to regular blood transfusions…

read more

Doxorubicin and cyclophosphamide mode of chemotherapy–related cardiomyopathy: Review of preclinical model

Apr 20, 2025 by in CARDIOLOGY Comments Off on Doxorubicin and cyclophosphamide mode of chemotherapy–related cardiomyopathy: Review of preclinical model

Abstract Over the past 70 years, there has been extensive research focused on preventing chemotherapy-related cardiovascular complications. However, the current state of cardio-oncology research has raised more questions than answers….

read more

Left atrial appendage occlusion devices vs direct oral anticoagulants for atrial fibrillation: An updated systematic review and meta-analysis

Apr 20, 2025 by in CARDIOLOGY Comments Off on Left atrial appendage occlusion devices vs direct oral anticoagulants for atrial fibrillation: An updated systematic review and meta-analysis

Abstract Background Direct Oral Anticoagulants (DOACs) are the first line anticoagulation for patients with non-valvular atrial fibrillation (NVAF). Percutaneous Left Atrial Appendage Occlusion (LAAO) has emerged as a new therapy…

read more

Heart transplantation in juvenile-onset systemic sclerosis with primary cardiac involvement: report of two cases and comprehensive literature review

Apr 20, 2025 by in CARDIOLOGY Comments Off on Heart transplantation in juvenile-onset systemic sclerosis with primary cardiac involvement: report of two cases and comprehensive literature review

Abstract Juvenile onset systemic sclerosis is a rare chronic multisystem connective tissue disease characterized by skin induration, microangiopathy, autoimmune disturbances and widespread fibrosis of internal organs. Primary cardiac involvement in…

read more

Prevalence and determinants of heart disease in Somaliland: An analysis of the 2020 Somaliland demographic and health survey (SLDHS)

Apr 20, 2025 by in CARDIOLOGY Comments Off on Prevalence and determinants of heart disease in Somaliland: An analysis of the 2020 Somaliland demographic and health survey (SLDHS)

Abstract Background Cardiovascular diseases (CVDs) are a leading cause of death globally, particularly in low- and middle-income countries. While data on heart disease prevalence in Somaliland is limited, the 2020…

read more

Ascertaining the prognostic role of cardiac resynchronisation therapy in cardiac sarcoidosis: A comparison with ischaemic cardiomyopathy

Apr 20, 2025 by in CARDIOLOGY Comments Off on Ascertaining the prognostic role of cardiac resynchronisation therapy in cardiac sarcoidosis: A comparison with ischaemic cardiomyopathy

Abstract Background Cardiac Resynchronisation Therapy (CRT) has demonstrated short and long-term benefit in heart failure with reduced ejection fraction (HFrEF), including ischaemic (ICM) and non-ischaemic cardiomyopathy. However, there is a…

read more
Get Clinical Tree app for offline access