Stem Cell-Based and Gene Therapies in Heart Failure

Jan 2, 2020 by in CARDIOLOGY Comments Off on Stem Cell-Based and Gene Therapies in Heart Failure

Outline Cardiac Cell Therapy, 599 Mechanisms of Action for Cardiac Cell Therapy, 599 Clinical Trials of Cardiac Cell Therapy, 603 Bone Marrow–Derived Mononuclear Cells, 603 Bone Marrow–Derived Mesenchymal Stem Cells,…

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Acute Heart Failure

Jan 2, 2020 by in CARDIOLOGY Comments Off on Acute Heart Failure

Nearly one third of acute heart failure (AHF) patients die or are rehospitalized within 90 days after discharge in the United States, with similar numbers in Europe. Despite a decade…

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Biomarkers and Precision Medicine in Heart Failure

Jan 2, 2020 by in CARDIOLOGY Comments Off on Biomarkers and Precision Medicine in Heart Failure

Outline Biomarkers: Definition and Guidelines for Evaluation, 449 Major Society Guidelines, 449 Heart Failure Biomarkers, 450 Myocardial Insult, 450 Myocardial Stretch, 450 Cardiac Necrosis, 456 Oxidative Stress, 457 Neurohormonal Activation,…

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Heart Failure as a Consequence of Hypertension

Jan 2, 2020 by in CARDIOLOGY Comments Off on Heart Failure as a Consequence of Hypertension

Outline Introduction: Definition and Impact, 333 Left Ventricular Hypertrophy, 333 Epidemiology, 333 Pathophysiologic Mechanisms, 334 Molecular Mechanisms, 335 Genetic Determinants of Left Ventricular Hypertrophy, 336 Classification and Diagnosis of Hypertensive…

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Heart Failure as a Consequence of Dilated Cardiomyopathy

Jan 2, 2020 by in CARDIOLOGY Comments Off on Heart Failure as a Consequence of Dilated Cardiomyopathy

Outline Definition, 269 Epidemiology of Dilated Cardiomyopathy, 270 Natural History of Dilated Cardiomyopathy, 270 Pathophysiology, 272 Diagnostic Strategies in Dilated Cardiomyopathy, 273 General Management Strategies of Dilated Cardiomyopathy, 273 Myocardial…

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Heart Failure as a Consequence of Congenital Heart Disease

Jan 2, 2020 by in CARDIOLOGY Comments Off on Heart Failure as a Consequence of Congenital Heart Disease

Outline Epidemiology, 363 Diagnosis, 363 Imaging, 364 Echocardiography, 364 Cardiac Magnetic Resonance Imaging, 364 Cardiopulmonary Exercise Testing, 364 Biomarkers, 365 Treatment, 366 Cardiac Resynchronization Therapy and Implantable Defibrillators in Adult…

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