Idiopathic Pulmonary Fibrosis: Diagnosis and Epidemiology

Mar 20, 2019 by in CARDIOLOGY Comments Off on Idiopathic Pulmonary Fibrosis: Diagnosis and Epidemiology

Abstract In 2000, the American Thoracic Society and European Respiratory Society published the first consensus statement providing guidelines on the diagnosis and treatment of idiopathic pulmonary fibrosis (IPF). This statement…

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Management of Idiopathic Pulmonary Fibrosis

Mar 20, 2019 by in CARDIOLOGY Comments Off on Management of Idiopathic Pulmonary Fibrosis

Abstract Idiopathic pulmonary fibrosis (IPF) is a relentlessly progressive and inevitably fatal lung disease. Although the etiology and pathogenesis of IPF remain incompletely understood, two drugs (e.g., pirfenidone and nintedanib)…

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Pathobiology of Novel Approaches to Treatment

Mar 20, 2019 by in CARDIOLOGY Comments Off on Pathobiology of Novel Approaches to Treatment

Abstract Comprehension of the pathobiology of any disease is crucial to identifying the cellular and molecular mechanisms through which that disease arises and evolves. This may lead to the discovery…

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Genetic Interstitial Lung Disease

Mar 20, 2019 by in CARDIOLOGY Comments Off on Genetic Interstitial Lung Disease

Abstract Technological advances have led to an explosion of genetic discoveries, shedding new light on the underlying pathogenesis of interstitial lung disease (ILD). Identification of the genetic etiology provides a…

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Meta-Analyses of Blood Pressure Lowering Trials and the Blood Pressure Lowering Treatment Trialists’ Collaboration

Mar 19, 2019 by in CARDIOLOGY Comments Off on Meta-Analyses of Blood Pressure Lowering Trials and the Blood Pressure Lowering Treatment Trialists’ Collaboration

Acknowledgments The authors would like to thank members of the Blood Pressure Lowering Treatment Trialists’ Collaboration: L. Agodoa (National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of…

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Updated American Heart Association/American College of Cardiology; European Society of Hypertension/European Society of Cardiology Guidelines

Mar 19, 2019 by in CARDIOLOGY Comments Off on Updated American Heart Association/American College of Cardiology; European Society of Hypertension/European Society of Cardiology Guidelines

United States of America Hypertension Guidelines (Portion) Background Story The groundwork for the first United States hypertension guideline began with the first randomized trial of hypertension treatment in U.S. veterans,…

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Putting All Guidelines Into Perspective

Mar 19, 2019 by in CARDIOLOGY Comments Off on Putting All Guidelines Into Perspective

Background The term “guideline” needs to be defined before any meaningful discussion can occur about their need and more importantly, interpretation. “Guideline” was originally defined as “a cord or rope…

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