Thoracic Key

Background Cardiovascular disease (CVD) is the major cause of human mortality and morbidity in developed countries and so that identification of new therapies is an important public health priority. Dysregulated…

Background Framingham risk score uses traditional risk factors to categorize patients according to their risk for cardiovascular events and to establish treatment guidelines. Aim To investigate the prevalence of coronary…

Background and objectives Increased arterial stiffness is an accepted cardiovascular risk factor. Several studies have shown that regular exercise is associated with reduced arterial stiffness. However, the acute effect is…

Background Framingham risk scores (FRS) are used to estimate the 10-year coronary heart disease (CHD) risk in individuals. Noninvasive assessment of subclinical atherosclerosis by means of carotid intima media thickness…

Background CYP3A5 has been reported to be an important genetic contributor to inter-individual and interracial differences in CYP3A-dependent drug clearance and response. The major determinant for this variation in expression…

Abstract We report the case of a 38-year-old man with a long-standing history of a small ventricular septal defect presented with chest pain. Electrocardiography revealed sinus rhythm, ST-segment elevation in…

Background The metabolic syndrome (metS), a concurrence of abdominal fat, disturbed glucose and insulin metabolism, dyslipidemia, and hypertension, has been strongly associated not only with subsequent development of type 2…

Background Randomized controlled trials report conflicting data about the beneficial effects of bone marrow cells for treating ischemic cardiovascular disease. Cell therapy also faces technical and practical limitations. Because evidence…

Abstract Symptomatic coronary artery disease may be commonly due to significant atherosclerotic disease involving coronary vessels of relatively small caliber (i.e., with reference vessel diameter <2.75 mm). Whenever medical therapy…