Background Diabetes mellitus (DM) plays a major role in the development and progression of coronary artery disease and negatively impacts clinical outcome in patients undergoing revascularization. Drug-eluting stents (DES) significantly…
Background Previous data suggests that patients presenting with acute coronary syndrome (ACS) who are on chronic clopidogrel have a poor prognosis possibly due to low response to clopidogrel. This study…
Background Little is known about the association between obesity and bleeding complications after percutaneous coronary intervention (PCI). We investigated the impact of body mass index (BMI) on PCI-related bleeding and…
Introduction While bivalirudin use in patients undergoing percutaneous coronary intervention (PCI) results in less bleeding compared to unfractionated heparin (UFH), its safety in patients undergoing rotational atherectomy (RA) is unknown….
Background The effects of angiotensin-converting enzyme inhibitors (ACEI) on the incidence of post-cardiac catheterization contrast-induced nephropathy (CIN) are not well understood. Some studies suggest that ACEI may contribute to CIN,…
Background Optimal platelet inhibition is critical to prevent ischemic events following percutaneous coronary intervention (PCI). However, recent studies have suggested that excessive inhibition may favor bleedings. We aimed to investigate…
Background While there is an agreement on the impact of door-to-balloon time as a prognostic factor, it is unknown whether the in-hospital outcome of patients with ST-segment elevation myocardial infarction…
Background Recent evidence shows that clopidogrel and proton pump inhibitors (PPI) are metabolized by the same pathway, and patients taking both drugs have higher levels of platelet reactivity and more…
Background Many studies have shown that a pharmacoinvasive strategy of urgent percutaneous coronary intervention following thrombolytic therapy in ST-segment elevation myocardial infarction (STEMI) patients is associated with better outcomes than…
Background Patients with chronic obstructive pulmonary disease (COPD) often present with pulmonary hypertension and right ventricular dysfunction. The impact of the reduction in cardiac reserve imposed by COPD on outcome…
