Introduction and General Principles

Jun 25, 2017 by in CARDIOLOGY Comments Off on Introduction and General Principles

, Edward Kiely2 and Imran Mushtaq3 (1) Department of Paediatric Surgery, Royal Hospital for Sick Children, Edinburgh, UK (2) Department of Paediatric Surgery, Great Ormond Street Hospital for Children NHS Foundation Trust,…

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The Proarrhythmic Cardiac Safety Regulatory Landscape Circa 2005–2015: Drug-Induced hERG Channel Block and the Thorough QT/QTc Study

Jun 25, 2017 by in CARDIOLOGY Comments Off on The Proarrhythmic Cardiac Safety Regulatory Landscape Circa 2005–2015: Drug-Induced hERG Channel Block and the Thorough QT/QTc Study

, Dilip R. Karnad2 and Snehal Kothari3 (1) Cardiac Safety Services Quintiles, Durham, North Carolina, USA (2) Research Team, Cardiac Safety Services Quintiles, Mumbai, India (3) Cardiac Safety Services Global Head, Cardiac Safety…

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Cardiovascular Structure, Function, and Pathophysiology

Jun 25, 2017 by in CARDIOLOGY Comments Off on Cardiovascular Structure, Function, and Pathophysiology

, Dilip R. Karnad2 and Snehal Kothari3 (1) Cardiac Safety Services Quintiles, Durham, North Carolina, USA (2) Research Team, Cardiac Safety Services Quintiles, Mumbai, India (3) Cardiac Safety Services Global Head, Cardiac Safety…

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Meta-analysis, Group Sequential Study Designs, Centralized Endpoint Adjudication, and Composite Endpoints

Jun 25, 2017 by in CARDIOLOGY Comments Off on Meta-analysis, Group Sequential Study Designs, Centralized Endpoint Adjudication, and Composite Endpoints

, Dilip R. Karnad2 and Snehal Kothari3 (1) Cardiac Safety Services Quintiles, Durham, North Carolina, USA (2) Research Team, Cardiac Safety Services Quintiles, Mumbai, India (3) Cardiac Safety Services Global Head, Cardiac Safety…

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Analyzing and Reporting Efficacy Data

Jun 25, 2017 by in CARDIOLOGY Comments Off on Analyzing and Reporting Efficacy Data

, Dilip R. Karnad2 and Snehal Kothari3 (1) Cardiac Safety Services Quintiles, Durham, North Carolina, USA (2) Research Team, Cardiac Safety Services Quintiles, Mumbai, India (3) Cardiac Safety Services Global Head, Cardiac Safety…

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Postmarketing Cardiovascular Safety Considerations

Jun 25, 2017 by in CARDIOLOGY Comments Off on Postmarketing Cardiovascular Safety Considerations

, Dilip R. Karnad2 and Snehal Kothari3 (1) Cardiac Safety Services Quintiles, Durham, North Carolina, USA (2) Research Team, Cardiac Safety Services Quintiles, Mumbai, India (3) Cardiac Safety Services Global Head, Cardiac Safety…

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Satisfying the Regulatory Requirements for New Antidiabetic Drugs for Type 2 Diabetes Most Expeditiously

Jun 25, 2017 by in CARDIOLOGY Comments Off on Satisfying the Regulatory Requirements for New Antidiabetic Drugs for Type 2 Diabetes Most Expeditiously

, Dilip R. Karnad2 and Snehal Kothari3 (1) Cardiac Safety Services Quintiles, Durham, North Carolina, USA (2) Research Team, Cardiac Safety Services Quintiles, Mumbai, India (3) Cardiac Safety Services Global Head, Cardiac Safety…

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Drug Structures and the Biological Basis of Drug Responses

Jun 25, 2017 by in CARDIOLOGY Comments Off on Drug Structures and the Biological Basis of Drug Responses

, Dilip R. Karnad2 and Snehal Kothari3 (1) Cardiac Safety Services Quintiles, Durham, North Carolina, USA (2) Research Team, Cardiac Safety Services Quintiles, Mumbai, India (3) Cardiac Safety Services Global Head, Cardiac Safety…

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