Fig. 6.1 ROS-mediated peroxidation of CL forming different molecular species of PUFA hydroperoxides. ROS causes peroxidation of linoleic acid in CL and forms monohydroperoxide and dihydroperoxides on one linoleate ester….
43. Shadel GS, Clayton DA. Mitochondrial DNA maintenance in vertebrates. Annu Rev Biochem. 1997;66:409–35.PubMed 44. Iborra FJ, Kimura H, Cook PR. The functional organization of mitochondrial genomes in human cells….
Fig. 16.1 This schematic places pulmonary vascular cell apoptosis, in particular endothelial cell apoptosis, in the center of the lung vascular remodeling process which results in exuberant wound healing. Autophagy…
Fig. 11.1 Proangiogenic hematopoietic cells may interact with resident endothelial progenitor cells to promote neoangiogenesis. Circulating hematopoietic (bone marrow-derived) cells are proposed to provide paracrine signals that stimulate resident endothelial…
Fig. 18.1 Mesenchymal stromal cell (MSC) differentiation was confirmed via multi-lineage differentiation. (a, b) WT and BMPR2 mutant iPSC were differentiated to MSC. Subsequent MSC were analyzed for their potential…
Fig. 9.1 Classification of endothelial cell colonies. Endothelial cell colonies are isolated from mononuclear cell fractions of cord blood, peripheral blood circulation, or derived from endothelial cell cultures after single…
Fig. 2.1 A model showing type II cell progenitor functions following alveoli injury. (a) Schematic representation of alveoli. (b) Section of mouse lung alveoli region stained by type II cell…
Fig. 13.1 (a) Immunofluorescence for CXCL12, CXCR4, CXCR7, and c-kit in mice lung exposed to chronic hypoxia (10 % oxygen for 3 weeks) or normoxia. Scale bars = 50 μm; (b) Pulmonary…
Fig. 17.1 Significant differences between early and late outgrowth EPCs. Most importantly, late outgrowth EPCs are highly proliferative and are able to independently form a vascular network. Early outgrowth EPCs…
Fig. 14.1 Pathobiology of pulmonary vascular remodeling in pulmonary hypertension. The pulmonary artery is normally characterized by a single endothelial monolayer, a smooth muscle medial layer, and an adventitial layer….
