Xience Nile, a real-life multicenter prospective Egyptian Xience V registry




Background


Previous demographic studies have revealed different CAD patterns among different population groups, with a more extensive and diffuse disease pattern among Egyptian/Arab patients particularly in a young age. These differences may be related to different risk factors distribution, socioeconomic factors or genetic aspects. DES performance is not adequately evaluated across different CAD patterns. The Xience V everolimus-eluting stent is a new-generation DES of proven safety and efficacy as shown in RCTs and multicenter registries.




Aim


The aim was to reproduce the safety and efficacy of the Xience V stent among Egyptian patients in a prospective multicenter all-comers registry.




Aim


The aim was to reproduce the safety and efficacy of the Xience V stent among Egyptian patients in a prospective multicenter all-comers registry.




Methods


A total of 426 consecutive patients were included in 20 centers; the exclusion criteria were very limited (primary PCI for STEMI, in-stent restenosis, using additional stents other than the study stent).


Primary endpoint


CMACE at 180 days: composite rate of all death, myocardial infarction (MI) and target vessel revascularization (TVR) at 180 days.


Secondary endpoints


MACE at 12 months: composite rate of cardiac death and MI at 6 and 12 months. Stent thrombosis as per ARC definition at 6 and 12 months.

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Nov 16, 2017 | Posted by in CARDIOLOGY | Comments Off on Xience Nile, a real-life multicenter prospective Egyptian Xience V registry

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