Venous vessel pathology — chronic cerebrospinal venous insufficiency in multiple sclerosis




Background


Multiple sclerosis (MS) is chronic inflammatory autoimmune disease of the CNS. MS is characterized by disseminated demyelinating lesions and axonal injury. At the beginning of disease dominates the inflammation and later the neurodegenerative processes. The established treatment of disease is limited to the relapsing–remitting course of the disease; for the patients with progressive course of disease, the therapy is solely symptomatic. Recently, the demonstration of the extracranial venous pathway stenoses has received great interest in scientific communities. The aim of our study was to detect the occurrence of venous stenosis in the group of MS patients with progressive course of disease.




Methods


In our study, we enrolled 30 consecutive MS patients with progressive course of disease (mean age 43.97±10.31). All patients fulfilled two of the five Doppler sonographic criteria required for CCSVI. After sonographic examination, selective venography through transfemoral route was performed.


Nov 16, 2017 | Posted by in CARDIOLOGY | Comments Off on Venous vessel pathology — chronic cerebrospinal venous insufficiency in multiple sclerosis

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