Randomized comparison of intracoronary eptifibatide vs. intracoronary tirofiban in primary percutaneous coronary intervention in patients with acute anterior ST-segment elevation myocardial infarction




Objectives


The aim of this study was to compare the intracoronary (IC) double bolus of eptifibatide and IC high bolus dose of tirofiban as adjuncts to primary percutaneous coronary intervention (PCI) in patients with anterior ST-segment elevation myocardial infarction (STEMI).




Background


GP IIb IIIa inhibitors improve the outcome in primary PCI. IC bolus of GP IIb IIIa inhibitors results in high local drug concentrations and may be more effective than a standard intravenous (IV) bolus. It remains unclear which of the two available GP IIb IIIa inhibitors in Egypt would be of great benefit when used as IC bolus.




Background


GP IIb IIIa inhibitors improve the outcome in primary PCI. IC bolus of GP IIb IIIa inhibitors results in high local drug concentrations and may be more effective than a standard intravenous (IV) bolus. It remains unclear which of the two available GP IIb IIIa inhibitors in Egypt would be of great benefit when used as IC bolus.

Only gold members can continue reading. Log In or Register to continue

Related posts:

  1. Understanding the impact of drug-eluting stent on vascular function and the nitric oxide pathway genes using a pig coronary artery stent implantation model
  2. Statin improves outcome of patients presenting with first acute myocardial infarction
  3. Risk factors and impact of contrast left ventriculogram on incidence of contrast-induced nephropathy: is left ventriculogram really necessary?
  4. Clinical outcomes and quality of life assessment of patients with diabetes mellitus undergoing surgical ablation of atrial fibrillation

Stay updated, free articles. Join our Telegram channel
Tags:
Nov 16, 2017 | Posted by in CARDIOLOGY | Comments Off on Randomized comparison of intracoronary eptifibatide vs. intracoronary tirofiban in primary percutaneous coronary intervention in patients with acute anterior ST-segment elevation myocardial infarction

Full access? Get Clinical Tree
Get Clinical Tree app for offline access