Introduction
Cocain is one of the most commonly used illicit drug which can cause myocardial ischemia or infarction. Cocaine use can cause acute coronary syndrome by inducing coronary vasoconstriction, thrombosis, dissection, positive sympathomimetic effects and direct myocardial toxicity. Recent American guidelines recommend to do urine toxicology screening for cocaine when substance abuse is suspected as a cause of or contributor to acute coronary syndrome, especially in younger patients. This study was aimed to investigate the reasonability of urine toxicology screening for cocaine in consecutive younger patients with acute coronary syndrome in Turkey.
Material and methods
Twenty patients younger than 50 years of age who admitted to coronary care unit with acute coronary syndrome were consecutively enrolled to the study. Mean age was 42±6 ( range 38-50 ). Male to female ratio was 5/12. Acute myocardial infarction with ST-segment elevation was diagnosed in 6 patients and acute coronary syndrome without persistent ST-segment elevation was diagnosed in 7 patients.. Urine samples of all patients were analyzed for cocaine.
Material and methods
Twenty patients younger than 50 years of age who admitted to coronary care unit with acute coronary syndrome were consecutively enrolled to the study. Mean age was 42±6 ( range 38-50 ). Male to female ratio was 5/12. Acute myocardial infarction with ST-segment elevation was diagnosed in 6 patients and acute coronary syndrome without persistent ST-segment elevation was diagnosed in 7 patients.. Urine samples of all patients were analyzed for cocaine.
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