Objective
Serum gamma-glutamyltransferase (GGT) and uric acid levels measured in patients with acute coronary syndrome without ST segment elevation (NSTEMI) are important in the diagnosis and in predicting the prognosis. There is a limited number of clinical studies investigating the effects of beta blockers on GGT and uric acid levels in these patients. In our study we aimed to investigate the effects of beta blocker therapy on GGT and uric acid levels.
Methods
Our study is randomized, prospective clinical study and 100 patients with NSTEMI were included in this study and patients were divided into two groups. 50 patients were administered metoprolol succinate treatment (1×50 mg) while the other 50 patients were administered carvedilol treatment (2×12.5 mg). Afterwards; all of the patients had coronary angiography. Blood samples were taken at the time of admission, at the first month and third month in order to detect GGT and uric acid levels.