Objective

Platelets, as an important actor in atherothrombosis, secrete a group of substances that play some crucial role in coagulation, inflammation and thrombosis. Platelet volume is a marker of platelet activation and measured by using mean platelet volume (MPV). Previous studies have shown that high MPV levels are associated with cardiovascular risk factors and acute myocardial infarction. In this present study we investigated the level of MPV in non ST elevation acute coronary syndrome (NSTE-ACS) and ST elevation acute coronary syndrome (STE-ACS) in emergency department.

Methods

The study population consisted of 100 consecutive patients admitted to the emergency department with angina or angina equivalent complaints within the first 12 hours of symptom onset. The diagnosis of ACS was made according to symptoms, ischemic changes in the ECG, and elevated cardiac biomarkers. A total of 60 NSTE-ACS and 40 STE-ACS patients were classified into groups 1 and 2, respectively. MPV was measured by auto analyzer. Diagnostic coronary angiography was performed in all patients using standart techniques.

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