Objective
Atherosclerosis plays an important role in the etiopathogenesis of coronary artery ectasia (CAE). Inflammation markers may play a part in the pathogenesis of CAE.The aim of this study is to investigate the association between platelet to lymphocyte ratio (PLR) and coronary artery ectasia (CAE).
Methods
61 patients (38 men) were diagnosed with CAE in coronary angiography, enrolled as the study group. 67 consecutive patients (37 men) who were diagnosed as normal coronary angiograms, were enrolled as the control group. These participants were evaluated using concurrent routine biochemical tests as well as neutrophil, lymphocyte, platelet counts, platelet to lymphocyte ratio (PLR) and neutrophil to lymphocyte ratio (NLR) which were obtained from the whole blood count. These parameters were compared between groups.
Methods
61 patients (38 men) were diagnosed with CAE in coronary angiography, enrolled as the study group. 67 consecutive patients (37 men) who were diagnosed as normal coronary angiograms, were enrolled as the control group. These participants were evaluated using concurrent routine biochemical tests as well as neutrophil, lymphocyte, platelet counts, platelet to lymphocyte ratio (PLR) and neutrophil to lymphocyte ratio (NLR) which were obtained from the whole blood count. These parameters were compared between groups.
Results
The baseline characteristics of the study groups were comparable. Platelet (262±58 x1000μL) and neutrophil (4769±1222 x1000μL) in the CAE group were significantly (p<0.05) higher than those (239±40 x1000μL, 3853±1080 x1000μL, respectively) in the control group. Lymphocyte count in the control group were significantly (p<0.05) higher than those in the CAE group (2521±530 vs 2424±581 x1000μL). The patients with coronary artery ectasia had a higher PLR and NLR than the control group (113±35 vs 97±19 and 2.0±0.7 vs 01.5±0.4; p<0.001 and 0.019), respectively.
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