Background
Inflammation markers may play a part in the pathogenesis of atherosclerosis and inflammatory reaction may play a role in-stent restenosis (ISR) after stent implantation. The aim of the our study was to investigate the predictive value of some inflammatory markers on development of in-stent restenosis in patients undergoing stent implantation.
Methods
Patients presenting with angiographically documented ISR (diameter stenosis ≥ 50% by visual estimation) were included as a study group(53 subjects) and the patients presenting with angiographically documented no ISR (diameter stenosis < 50% by visual estimation) as a control group(53 subjects). There were 15/9 females/males in control group and 38/44 females/males in study group. There were 13 patients witn diabetes mellitus in control group and 16 patients in study group. The whole groups were compared with age, lipid profiles and fasting levels of glucose. Also, hematologic parameters were measured as part of the automated complete blood count.
Methods
Patients presenting with angiographically documented ISR (diameter stenosis ≥ 50% by visual estimation) were included as a study group(53 subjects) and the patients presenting with angiographically documented no ISR (diameter stenosis < 50% by visual estimation) as a control group(53 subjects). There were 15/9 females/males in control group and 38/44 females/males in study group. There were 13 patients witn diabetes mellitus in control group and 16 patients in study group. The whole groups were compared with age, lipid profiles and fasting levels of glucose. Also, hematologic parameters were measured as part of the automated complete blood count.
Results
There were no statistically significant differences in baseline charecteristics between two groups. Platelet-lymphocyte ratio (PLR), lymphocyte count, lymphocyte-platelet distrubition width ratio (LPR) were not significantly higher in patients with study group compared with those of controls. But, white blood counts, neutrophil counts and neutrophil and lymphocyte ratio(N/L ratio) were significantly higher in patients with study group compared with those of controls (Table-1).
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