OP-173 Evaluation of the Torsion and Twist Mechanics of the Left Ventricle in Patients with Systemic Lupus Erythematosus




Objective


Myocardial involvement in systemic lupus erythematosus (SLE) has a great importantance. Therefore, the aim of this study is to evaluate the rotation and twisting mechanics of the left ventricle (LV) in patients with SLE.




Methods


Forty -three patients fulfilled at least four of the American College of Rheumatology criteria for SLE with systemic lupus erythematosus (SLE) and thirty individuals as a control group were enrolled the study. LV ejection fraction was calculated by biplane Simpson’s method. Measurement of strain and rotational parameters was performed offline.




Methods


Forty -three patients fulfilled at least four of the American College of Rheumatology criteria for SLE with systemic lupus erythematosus (SLE) and thirty individuals as a control group were enrolled the study. LV ejection fraction was calculated by biplane Simpson’s method. Measurement of strain and rotational parameters was performed offline.




Results


The values of mean global longitudinal strain (GLS), global circumferential strain (GCS) basal, mean radial strain (RS) basal and GCS apical were significantly lower in SLE patients when compared with normal myocardium in the control group. (-20.0 ± 3.0 vs. -22.4 ± 3.1, p= 0.002, -15.3 ± 5.1 vs. -20.3 ± 3.6, p<0.001, 40.7 ± 19.4 vs. 51.5 ± 15.8, p= 0.015, -25.0 ± 7.8 vs. -28.8 ± 5.5,p= 0.030, respectively. The difference between basal rotation, apical rotation, twist and torsion of the left ventricle in SLE patients and the control group were not significant (11.7 ± 6.4 vs. 13.2 ± 6.4, p= 0.366, 1.8 ± 0.8 vs. 1.9 ± 2.3, p= 0.725, respectively). There was not any significant relationship between SELENA-SLEDAI score and myocardial strain analyses and twist mechanics of the left ventricle in patients with SLE.

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Nov 30, 2016 | Posted by in CARDIOLOGY | Comments Off on OP-173 Evaluation of the Torsion and Twist Mechanics of the Left Ventricle in Patients with Systemic Lupus Erythematosus

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