Methods
A total of 88 patients (57 male, 64.8 %; mean age 38.6±17.7) with the diagnosis of NCM were enrolled and followed up during median 42.4 months. fQRS was defined as the presence of ≥1 additional R wave (R′) or notch on the R/S waves in QRS complexes in ≥2 contiguous leads representing anterior (V1–V5), inferior (II, III, aVF), or lateral (I, aVL, V6) myocardial segments.
Methods
A total of 88 patients (57 male, 64.8 %; mean age 38.6±17.7) with the diagnosis of NCM were enrolled and followed up during median 42.4 months. fQRS was defined as the presence of ≥1 additional R wave (R′) or notch on the R/S waves in QRS complexes in ≥2 contiguous leads representing anterior (V1–V5), inferior (II, III, aVF), or lateral (I, aVL, V6) myocardial segments.
Results
Compared with the fQRS (-) patient group, patients with fQRS (+) showed higher rates of total arrhythmic events, ventricular tachycardias, bradyarrhythmias requiring pacemaker, sudden cardiac death, cardiovascular and all-cause mortality. The cut-off point of ≥3 leads for the fQRS was the optimal point discriminating the arrhythmic events and cardiovascular mortality. In Kaplan-Meier survival analysis, total arrhythmic events and cardiovascular mortality occurred more frequently in the fQRS (+) group. In multivariate Cox proportional hazard regression analysis, adjusted with other factors, the presence of fQRS were determined as an independent predictor of arrhythmogenic events (HR: 3.850, 95% CI: 1.062–9.947, p=0.002), and cardiovascular mortality (HR: 2.719, 95% CI: 1.494–9.262, p=0.005).
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