OP-077 Assessment of Pulmonary Atrerial Stiffness in Obstructive Sleep Apnea




Purpose


Pulmonary hypertension (PH) is one of the major complications of obstructive sleep apnea syndrome (OSAS). Pulmonary arterial stiffness (PAS) can be used in determination of PH. The aim of the present study was to evaluate the PAS and cardiac function of patients with OSAS and analyse the relationship between OSAS severity and PAS.




Methods


Sixty newly diagnosed patients with OSAS (mean age 49.6±11.7 years) and thirty healthy controls (mean age 46.4±14 years) were enrolled. Right ventricle (RV) and left ventricle (LV) echocardiographic parameters and PAS values of study groups were compared.




Methods


Sixty newly diagnosed patients with OSAS (mean age 49.6±11.7 years) and thirty healthy controls (mean age 46.4±14 years) were enrolled. Right ventricle (RV) and left ventricle (LV) echocardiographic parameters and PAS values of study groups were compared.




Results


There were no significant differences in terms of LV ejection fraction, LV tei-index and tricuspid annular plane systolic excursion (TAPSE). PAS, mean pulmonary arterial pressure (PAP) and RV tei-index were significantly higher but tricuspid annulus early diastolic myocardial velocity was lower in patients with OSAS than control subjects (respectively p < 0.001, p < 0.001, p = 0.001, p = 0.001). Moreover, we found a higher PAS in OSAS patients without PH compared to controls (p < 0.001). When we investigated the relationship between polysomnographic variables and echocardiographic parameters, we found positive correlations between apnea hypopnea index (AHI) and total oxygen desaturation with PAS and mean PAP (r= 0.384, p< 0.001; r=0.404, p<0.001; r=0.36, p<0.001; r=0.349, p=0.001 respectively).

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Nov 27, 2016 | Posted by in CARDIOLOGY | Comments Off on OP-077 Assessment of Pulmonary Atrerial Stiffness in Obstructive Sleep Apnea

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