Methods
The study is based on management of 136 patients with definite ANVIE as defined by the Duke criteria. According to certain criteria one of two mutually exclusive conclusions was done in 106 of them before surgery: unfavorable course of ANVIE or (favorable course conditionally). Multivariate backward stepwise binary logistic regression analysis was used to identify the independent predictors of unfavorable course of ANVIE in them as well to identify the independent predictors of 6-month mortality (in 136 patients). Since 2007 a new approach including assessment of cardiosurgery risk by EuroSCORE and isolated medical treatment risk is used for management optimization of active native valve infective endocarditis (main group – 68 consecutive patients) compared to conventional management during 2004–2006 years (42 consecutive patients in the same departments). Kaplan-Meier method with the log-rank test was used to compare survival in groups.
Methods
The study is based on management of 136 patients with definite ANVIE as defined by the Duke criteria. According to certain criteria one of two mutually exclusive conclusions was done in 106 of them before surgery: unfavorable course of ANVIE or (favorable course conditionally). Multivariate backward stepwise binary logistic regression analysis was used to identify the independent predictors of unfavorable course of ANVIE in them as well to identify the independent predictors of 6-month mortality (in 136 patients). Since 2007 a new approach including assessment of cardiosurgery risk by EuroSCORE and isolated medical treatment risk is used for management optimization of active native valve infective endocarditis (main group – 68 consecutive patients) compared to conventional management during 2004–2006 years (42 consecutive patients in the same departments). Kaplan-Meier method with the log-rank test was used to compare survival in groups.
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