Objective
Abnormal hemostatic and platelet activation parameters have been reported in patients with AF. However, whether activation of platelets via Toll- like receptors has a role in AF persistency has not been evaluated yet. In this study, we aimed to investigate whether peripheral platelet Toll-like receptor (TLR) expression was associated with type of AF.
Methods
Patients with AF who were scheduled for cryoballoon- based ablation were included. Peripheral platelet TLR- 2 and 4 expression were evaluated by flow cytometric analysis in peripheral venous blood samples.