Objective
Epicardial adipose tissue is associated with coronary artery disease, metabolic syndrome and atrial fibrillation. Increased epicardial adipose tissue thickness (EATT) has been found recently to be significantly correlated with ischemic stroke and useful in the estimation of the risk of stroke. CHADSVASc score is a well-validated clinical risk stratification tool used in patients with non-valvular atrial fibrillation to calculate stroke risk. The aim of this study was to investigate whether there is a relation between EATT and CHADSVASc score.
Methods
This prospective study included 269 consecutive patients (median age 66 years) with non-valvular atrial fibrillation detected by ECG or 24-hour Holter ECG. All patients underwent a transthoracic echocardiography to measure EATT and the CHADSVASc score was calculated. Data was presented as median (25/75% interquartile range).
Methods
This prospective study included 269 consecutive patients (median age 66 years) with non-valvular atrial fibrillation detected by ECG or 24-hour Holter ECG. All patients underwent a transthoracic echocardiography to measure EATT and the CHADSVASc score was calculated. Data was presented as median (25/75% interquartile range).
Results
CHADSVASc scores were 0 in 15 patients (5.6%), 1 in 52 (19.3%), 2 in 69 (25.7%), 3 in 55 (20.4%), 4 in 34 (12.6%), 5 in 20 (7.4%), 6 in 12 (4.5%), 7 in 9 (3.3%), 8 in 2 (0.7%), and 9 in 1 patient (0.3%). Comparison of EATT to criteria of CHADSVASc scoring is presented in table 1. EATT was higher in patients with a history of stroke/transient ischemic attack/thrombo-embolism than in those without [6.5 (4.1/8.3) mm vs. 4.7 (3.5/6) mm, p < 0.001]. In addition, EATT was significantly correlated with CHADSVASc score (r = 0.433, p <0.001). Linear regression analysis revealed that an EATT of ≥4.12 mm and ≥4.76 mm predict CHADSVASc scores 1 and 2, respectively (B = 0.639, Constant = 3.486, p < 0.001).
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