Objective
Metabolic syndrome (MS) is defined by a cluster of interdependent physiological, biochemical and clinical risk factors and linked to a state of chronic low grade inflammation. YKL-40 is known as an inflammatory glycoprotein which is secreted by various cell lines during inflammation. Thus, we aimed to assess the association of serum YKL-40 levels with the presence and severity of MS.
Methods
In this prospective cross-sectional study, a total 186 consecutive patients [n=122 MS present and n=64 MS absent] were enrolled. MS was defined according to NCEP-ATP III criteria. Serum YKL-40 and hs-CRP levels were measured for all participants. Independent predictors of MS were determined by logistic regression analysis.
Methods
In this prospective cross-sectional study, a total 186 consecutive patients [n=122 MS present and n=64 MS absent] were enrolled. MS was defined according to NCEP-ATP III criteria. Serum YKL-40 and hs-CRP levels were measured for all participants. Independent predictors of MS were determined by logistic regression analysis.
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