Aims
The objectives were to: (i) evaluate endothelial function via fingertip reactive hyperemia peripheral arterial tonometry (RH-PAT) among heart failure (HF) patients receiving cardiac resynchronization therapy (CRT), (ii) assess the effects of CRT on RH-PAT score, (iii) investigate whether RH-PAT score can identify CRT response.
Methods
A total of 63 patients (61.8 ± 10.3 years; 51 males; left ventricular ejection fraction 24.3 ± 3.9%) with HF who implanted CRT were enrolled. Endothelial function via RH-PAT was assessed 1 day before and 6 months after CRT. A RH-PAT score <1.7 signified a cut-off for endothelial dysfunction (ED). Minnesota Living with Heart Failure Questionnaire (MLWHFQ) was used to assess clinical improvement. CRT response was defined as a reduction in left ventricular (LV) end-systolic volume (LVESV) ≥15% at 6th month.

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