Objective
N-terminal pro-Brain Natriuretic Peptide (NT-proBNP) is associated with atrial fibrillation (AF) in the setting of acute ST-elevation myocardial infarction (STEMI). The aim of this study was to assess the predictive value of serial NT-proBNP levels in identifying STEMI patients at risk of developing incident AF.
Methods
830 patients enrolled in On-TIME II were included. NT-proBNP was assessed at baseline, 24h and 72h after admission for STEMI. Patients with new-onset, incident AF <30 days after STEMI were divided depending on the timing of the first AF episode among 3 subgroups: AF on admission, AF 24-72h after admission and AF >72h after admission. ROC analysis and binary logistic regression were performed.
Methods
830 patients enrolled in On-TIME II were included. NT-proBNP was assessed at baseline, 24h and 72h after admission for STEMI. Patients with new-onset, incident AF <30 days after STEMI were divided depending on the timing of the first AF episode among 3 subgroups: AF on admission, AF 24-72h after admission and AF >72h after admission. ROC analysis and binary logistic regression were performed.
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