Coronary artery disease (CAD) is a main leading cause of death worldwide in general, and in the the developing countries in particular, some of the risk factors for developing CAD are known, some others are not well studied including Hepatitis C virus seropositivity which is predominant in most of the developing countries.
100 patients coming for coronary angiography were studied in 3 years. They were divided into 2 groups according to coronary angiography findings into Normal or “control group” (50 patients) and Abnormal group (50 patients), each group was subdivided into 2 subgroups according to Hepatitis C virus infection into negative and positive subgroups.
The age population in this study was ranging from 20 to 60 years old, with 57 male (57%) and 43 female (43%). There residences ranged from 68% from rural areas and 32% from urban areas, all other well known risk factors for CAD were matched between normal and abnormal groups including (DM, HTN and smoking) making the HCV infection is the only factor that can affect the coronary artery status. The incidence of HCV infection was higher in the group with abnormal coronary than in the group with normal coronary, the difference was statistically significant (46% vs 14%, P < 0.03), this indicate a relation between the coronary artery diseases and the HCV infection. More vessels were found diseased in the in the hepatitis C positive group, compared to the negative group with statistically significant difference (P <0.02)