Long-term follow-up of mitral valvuloplasty with single balloon, independent predictors of survival and event-free survival




Objectives


The objectives were to evaluate long-term follow-up (FU) of mitral balloon valvuloplasty (MBV) with single balloon (SB), the less expensive technique to perform MBV, and to determine independent predictors of survival and event-free survival (EFS).




Methods


From 1987 to December 31, 2008, 524 procedures of MBV were performed, 404 (77.1%) with SB Balt, with 256 procedures with long-term FU. The final balloon diameter was 25 mm in 5 procedures and 30 mm in 251; mean dilatation area was 7.02±0.30 cm 2 . The FU was 54.6±32.8 (1–174) months. To determine independent predictors of survival and EFS, the multivariate Cox analysis was used.


Results


Mean age was 38.0±12.6 (13 to 83) years, with 222 (86.7%) being female; 215 (84.0%) patients were in sinus rhythm; echo score was 7.2±1.5 (4 to 14) points; and echo mitral valve area (MVA) pre-MBV was 0.93±0.21 cm 2 . Mean pre- and post-MVAs (Gorlin) were 0.90±0.20 and 2.02±0.37 cm 2 ( P <.001) and success MVA ≥1.5 cm 2 in 241 (94.1%) procedures and mean pulmonary artery pressures pre- and post-MBV were 27±10 and 20±7 mmHg . Three (1.2%) patients began the FU with severe mitral regurgitation (MR). At the end of the FU, 119 (46.5%) patients were in NYHA FC I, 70 (27.3%) were in FC II, 53 (20.7%) were in FC III, 3 (1.2%) were in FC IV and there were 11 deaths (4.3%). At the end of the follow-up, there were 17 (8.2%) patients with new severe MR, 12 (4.7%) were submitted to new MBV, 27 (10.5%) had mitral valve surgery and 70 (26.3%) used no medication at the end of the FU. Independent predictors of survival were echo score ≤8 ( P <.001, HR=0.116), age ≤50 years old ( P =.011, HR 0.203) and absence of mitral surgery in the evolution ( P =.004, HR 0.170). Independent predictors of EFS were absence of prior commissurotomy ( P <.002, HR 0.318), female gender ( P =.036, HR 0.466) and MVA post-MBV ≥1.50 cm 2 ( P <.001, HR 0.466).

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Nov 16, 2017 | Posted by in CARDIOLOGY | Comments Off on Long-term follow-up of mitral valvuloplasty with single balloon, independent predictors of survival and event-free survival

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