Background
Patients presenting with ST-elevation myocardial infarction (STEMI) have different clinical outcomes based on their clinical baseline characteristics and presentation. This study was aimed to determine the importance of lesion location of the culprit vessel on mortality and the 1-year cardiovascular events.
Methods
The study comprised 700 consecutive patients with STEMI who underwent primary percutaneous coronary intervention (PCI) for the culprit lesion. Patients were divided into two groups regarding the vessel location of the culprit lesion: left anterior descending artery (LAD) group ( n =321) vs. non-LAD group ( n =379). The patients who underwent multilesion PCI or multivessel PCI and those with left main coronary artery disease were excluded. The clinical outcome in hospital and at 1 year was recorded.
Methods
The study comprised 700 consecutive patients with STEMI who underwent primary percutaneous coronary intervention (PCI) for the culprit lesion. Patients were divided into two groups regarding the vessel location of the culprit lesion: left anterior descending artery (LAD) group ( n =321) vs. non-LAD group ( n =379). The patients who underwent multilesion PCI or multivessel PCI and those with left main coronary artery disease were excluded. The clinical outcome in hospital and at 1 year was recorded.
Results
The baseline characteristics were similar between the two groups. In-hospital mortality was significantly higher in the LAD group than the non-LAD group (8.7% vs. 4.7%, P =.03), as was total 1-year mortality ([15.0% vs. 10.3%, P =.06). After adjustment for baseline, angiographic or procedural characteristics, culprit lesion located in LAD remained an independent predictor for 1-year MACE ( Table 1 ).
