High transvalvular gradient vs. low transvalvular gradient in patients with severe aortic stenosis and poor left ventricular function




Background


Left ventricular systolic dysfunction in patients with severe aortic stenosis (AS) is associated with poor outcome. The aim was to compare the outcome of patients with severe AS and low ejection fraction (EF) with high vs. low transvalvular gradients.




Methods


A total of 193 patients with severe AS and low EF <40% who were referred to participate in the clinical trial of transcatheter aortic valve implantation (TAVI) were studied. Patients were divided into two groups: group I with low mean transvalvular gradient <40 mmHg ( N =103) and group II with high transvalvular gradients ≥40 mmHg ( N =90). Clinical, hemodynamic and follow-up mortality data were collected.




Methods


A total of 193 patients with severe AS and low EF <40% who were referred to participate in the clinical trial of transcatheter aortic valve implantation (TAVI) were studied. Patients were divided into two groups: group I with low mean transvalvular gradient <40 mmHg ( N =103) and group II with high transvalvular gradients ≥40 mmHg ( N =90). Clinical, hemodynamic and follow-up mortality data were collected.

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Nov 16, 2017 | Posted by in CARDIOLOGY | Comments Off on High transvalvular gradient vs. low transvalvular gradient in patients with severe aortic stenosis and poor left ventricular function

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