26 Echocardiographic Guidance of Procedures
Jugular Venous Cannulation
Sequence
Place the patient in Trendelenburg position to increase the size of the neck veins.
With the skin cleaned and sterile, introduce the probe into a sterile plastic sheath.
Image from the anterior neck in the mid-portion, which overlies the internal jugular vein and the common carotid artery. The jugular vein, depending on the central venous pressure, may be (usually is) larger than the common carotid artery, but in volume-contracted or dehydrated patients, the vein may be smaller than the artery. The vein may lie to the side of, anterolateral to (this is its usual location in the mid-neck), anterior but slightly lateral to, or completely anterior to the artery.
The most desirable site for cannulation is where the vein is substantially at least lateral to the artery, so that inadvertent transfixion of the vein runs little risk of inadvertently puncturing the common carotid artery. Avoid locations where the jugular vein is directly anterior to the artery.
The vein is identified by the following:
If the vein is generously full, the needle is inserted carefully through the taut anterior wall of the vein until the tip is a few millimeters into the lumen.
If the vein is full but limp, have the patient make a partial Valsalva maneuver to distend the vein, providing a larger target for the needle puncture and a more taut anterior wall.
It is easiest if the patient is told to take a breath (inspire) before he or she is told to strain (perform a Valsalva maneuver). Guiding the patient in practicing the performance of a Valsalva maneuver before the procedure is helpful for patients who are not familiar with it.
Visualize the wire extending from the needle.
Visualize the sheath within the lumen following its insertion.
Be aware of the presence of jugular venous valves, a normal aspect of anatomy. Insertion beneath the valves may simplify the procedure.
Be aware of the appearance of jugular venous thrombus, a common residua of prior catheter and wire insertions
Endomyocardial Biopsy
To reliably diagnose heart transplant rejection, right ventricular endomyocardial biopsy (percutaneous procurement of endomyocardial samples from the right ventricle1,2) remains the gold standard. Right ventricular endomyocardial biopsy also is a valuable way to assist with diagnosis and management of suspected myocarditis, infiltrative cardiomyopathy, or other unexplained ventricular dysfunction.
Percutaneous right ventricular endomyocardial biopsy most commonly is performed using cannulation of the right internal jugular vein. In circumstances where this vessel is not usable, the femoral vein can be used for this purpose. Cardiologists traditionally have relied on fluoroscopic guidance for placement of the bioptome. Using frontal-plane fluoroscopic guidance, the bioptome is directed toward the right ventricular septum to obtain right ventricular samples. Bioptome contact with the right ventricular septum is confirmed by the presence of ventricular ectopic beats, and samples are taken from that site. Typically at least four biopsy samples are obtained, because a minimum of three adequate biopsy samples are required for histologic diagnosis. The use of fluoroscopy to guide right ventricular endomyocardial biopsy has a number of drawbacks: it provides only approximate bioptome placement information; exposes both the patient and physician to radiation; and requires use of the cardiac catheterization laboratory—a facility in high demand. Using fluoroscopic guidance, the complication rate ranges from 6% to 14%,3,4 with possible complications including myocardial perforation, tricuspid valve apparatus disruption, arrhythmias, coronary artery to right ventricular fistula, and inadvertent arterial punctures. A significant limitation of fluoroscopic guidance for right ventricular endomyocardial biopsies is that the bioptome placement and subsequent sampling area are limited due to inability to place the bioptome precisely, leading to repeated sampling from the same area. This contributes to biopsies that consist predominantly of scar from previous biopsy sites, which are inadequate for histologic assessment, and to reduced sensitivity due to the potentially focal nature of rejection or other cardiac histologic processes.
Sequence
Echocardiographically guided endomyocardial biopsy usually is performed in the echocardiography laboratory, with the assistance of an echosonographer and a nurse.
The person performing the biopsy procedure stands at the head of the bed, with the echosonographer and echocardiography machine to the patient’s left and the nurse and sterile tray to the patient’s right.
Echocardiographic images are obtained prior to venous cannulation to determine the optimal window and views for visualization of the right atrium and ventricle; to briefly assess left and right ventricular systolic function, the presence and amount of pericardial fluid present, and the presence and degree of tricuspid regurgitation; and to estimate right ventricular systolic pressure. Preprocedure imaging also determines the ideal patient positioning. In many cases supine imaging is adequate, but patients may be moved into the left lateral lying position after initial insertion of the jugular venous sheath to optimize visualization of the right-sided cardiac structures. Ultrasound assessment of the right internal jugular vein may be done at this time, to assist in venous cannulation.
Venous access is obtained using standard Seldinger technique via the right internal jugular vein, with a sheath left in place.
The bioptome is then inserted through the venous sheath into the right atrium.
Using echocardiographic imaging to visualize the right-sided chambers and tricuspid valve and apparatus, the bioptome is then passed across the tricuspid valve into the right ventricle. The endocardial surfaces of the right ventricle are visualized, and the sonographer “follows” the advancement of the bioptome, keeping the forceps head of the bioptome clearly imaged throughout the procedure. The operator maneuvers the bioptome to the desired location, avoiding the moderator band and tricuspid apparatus. Once the bioptome is approximated next to the endomyocardial surface in the desired position, the jaws of the bioptome are opened, and the bioptome is advanced gently against the endomyocardium. Once in place, the jaws are closed and, with a very gentle tug, the biopsy sample is obtained. The bioptome is removed, the sample is placed in sterile saline, and the procedure is repeated until an adequate number of samples have been obtained.
Samples may be taken from the mid to distal right ventricular septum, apex, and free wall in post–cardiac transplant patients, but are usually restricted to the mid- to distal right ventricular septum in non–transplant patients.
Post-procedure echocardiographic imaging assesses for changes in the presence or degree of tricuspid regurgitation and/or pericardial fluid.
Two decades ago, Miller published his successful results using echocardiographic guidance for right ventricular endomyocardial biopsy.5 Despite this and other reports of reduced costs and an improved safety profile using echocardiography to guide right ventricular endomyocardial biopsy in adults and children,6–10 this technique has not gained widespread popularity.
Pros
Provision of additional information
Despite valid and compelling benefits, there has been reluctance to adopt echocardiographically guided right ventricular biopsy. A typical argument against the technique is the perception that it is difficult to get adequate echocardiographic images in some patients. In 90% of patients, however, the standard apical four-chamber view can be used to view the bioptome head,6 although modifications of this view may be necessary to provide optimal imaging during bioptome manipulation.
Pericardiocentesis
Sequence
Unlike chest CT scan, real-time imaging by echocardiography of the heart’s motion within the pericardial space enables determination of the dimension of pericardial fluid throughout the cardiac cycle, which can vary considerably between diastole and systole.
During the procedure, use of a sterile sleeve to enable scanning immediately beside the site of puncture allows for real-time imaging.
Pros
Portability: can be performed at any bedside
Real-time imaging during the procedure maximizes procedural awareness.
Transseptal Puncture
Rationale and Role
Visual guidance by transesophageal echocardiography (TEE) of interatrial septal puncture to lessen risk of inadvertent puncture complications and identify any complications that do occur
Guidance of complex transseptal punctures in cases of kyphosis or scoliosis where the heart orientation (specifically that of the interatrial septum) within an abnormal chest cavity is unclear without imaging
Sequence
Visualization of the catheter and needle approaching the heart (inferior vena cava/bicaval view)
Visualization of the needle contacting the interatrial septum away from the margin of the septum
Visualization of the needle tenting the interatrial septum away from the margin of the septum
Visualization of the needle/catheter in the left atrium
Visualization of the catheter flush (small bubbles) in the left atrium
Catheter Mitral Balloon Valvuloplasty
Percutaneous Aortic Valvuloplasty
Sequence
Preprocedural Assessment
Severity/morphology of aortic stenosis
Routine transthoracic echocardiography (TTE) is done to assess for aortic stenosis, including ensuring that the stenosis is valvular and determining, at a minimum, the valve gradient and aortic valve area. (Other values such as the dimensionless index may be helpful in some situations.)