Correlation between fractional flow reserve and intravascularultrasound lumen area in intermediate coronary artery stenosis




Background


Clinical decision making in patients with intermediate coronary stenosis is still debated. Deferring intervention based on intravascular ultrasound (IVUS) guidance of minimal luminal cross-sectional area (MLA) ≥4 mm 2 or fractional flow reserve (FFR) >0.8 is associated with a low event rate.




Aim


The aim was to assess whether there is an IVUS anatomical measurement that can reliably be used to predict physiological significance of FFR <0.8.




Aim


The aim was to assess whether there is an IVUS anatomical measurement that can reliably be used to predict physiological significance of FFR <0.8.




Methods


The analysis included 150 intermediate lesions (134 patients) defined as 40%–70% stenosis based on quantitative coronary angiogram. These lesions were evaluated by a pressure guidewire and IVUS. Cutoff for positive FFR for ischemia was <0.80. Patients with acute myocardial infarction, saphenous vein graft lesions, lesions in vessels <2.5 mm in diameter or >1 lesion in the vessel studied were excluded.

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Nov 16, 2017 | Posted by in CARDIOLOGY | Comments Off on Correlation between fractional flow reserve and intravascularultrasound lumen area in intermediate coronary artery stenosis

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