Combined intracoronary tirofiban and manual thrombectomy during primary percutaneous coronary intervention in patients with ST-segment elevation myocardial infarction




Background


This study assessed the probable synergistic effect of combination of intracoronary (IC) tirofiban and manual thrombectomy (MT) during primary percutaneous coronary intervention (pPCI) in patients with acute ST-elevation myocardial infarction (STEMI).




Methods


Forty patients with STEMI were divided into two groups (A and B): Group A (20 patients) received IC bolus of tirofiban (25 µg/kg) plus MT, while group B patients underwent pPCI with an intravenous (IV) bolus of tirofiban (25 µg/kg) and no MT. Subsequently, both groups received IV tirofiban infusion for the next 16 h (0.15 µg/kg/min). Both groups had similar baseline clinical characteristics and door to balloon time.




Methods


Forty patients with STEMI were divided into two groups (A and B): Group A (20 patients) received IC bolus of tirofiban (25 µg/kg) plus MT, while group B patients underwent pPCI with an intravenous (IV) bolus of tirofiban (25 µg/kg) and no MT. Subsequently, both groups received IV tirofiban infusion for the next 16 h (0.15 µg/kg/min). Both groups had similar baseline clinical characteristics and door to balloon time.

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Nov 16, 2017 | Posted by in CARDIOLOGY | Comments Off on Combined intracoronary tirofiban and manual thrombectomy during primary percutaneous coronary intervention in patients with ST-segment elevation myocardial infarction

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