Postoperative nausea and vomiting
Analgesics
Corticosteroids (for prophylaxis)
Barbiturates
Transdermal scopolamine
Benzodiazepines
Metoclopramide
Hypnotics (i.e., zolpidem)
Promethazine
Pentazocine
Prochlorperazine
Meperidine
Skeletal muscle relaxants
Non-COX NSAIDs
Optimum fluid management in the operating room is essential in older adults because of the physiologic and disease-related changes in the cardiovascular function that accompany aging. Maintaining adequate cardiac output and end-organ perfusion becomes challenging when the effects of vasoactive anesthetic agents are combined with these changes. The autonomic nervous system, myocardium, and arterial and venous vasculature are all impacted by age in a manner that challenges hemodynamic stability during surgery [64]. The sympathetic portion of the autonomic nervous system becomes desensitized to beta-receptor stimulation, limiting the myocardial contractility and heart rate in response to hypovolemia [65, 66]. Arteries become stiff and calcified, increasing outflow resistance and leading to ventricular hypertrophy. This, combined with other changes in myocyte cellular function, leads to impaired cardiac relaxation and diastolic dysfunction. The aging heart is therefore increasingly reliant on preload and atrial contraction to maintain cardiac output [65, 66]. Hemodynamic stability is easily compromised with atrial fibrillation, where the atrial component of filling is absent [64, 66].
Older adults are also at an increased risk for intraoperative hypothermia owing to age-related changes in hypothalamic temperature regulation and peripheral vascular reactivity, and to decreased lean muscle mass (sarcopenia) and basal metabolic rate [63]. Hypothermia i n the operating room increases the likelihood of developing pressure ulcers, surgical site infections, cardiac events, and coagulopathy requiring blood transfusion [63, 67–69]. Intraoperative hypothermia (temperature <36 °C) should be avoided by keeping the operating room at an appropriate temperature , using fluid warmers and forced warm air blankets.
Role of the Operating Room Nursing Team
Safe and proper patient handling and positioning on the operating table to avoid undue pressure is of paramount importance in the older adult. A pressure ulcer is a devastating but preventable complication, which has been shown to significantly increase morbidity and mortality and decrease quality of life [70]. Proper alignment, positioning, padding, and pressure-relieving devices all contribute to maintaining adequate arterial blood flow to pressure points [71]. Patients aged over 65 experience the highest incidence of pressure ulcer development owing to age-related changes in skin and inadequate nutrition. Transfers should always be performed using a lateral transfer device to reduce friction and shear force and protect against accidental skin damage [71].
Postoperative Phase
The key to successful management of the geriatric surgical patient is the prevention of postoperative complications. In addition to the usual surgical complications, such as surgical site infections, older adults are at increased risk of “geriatric complications” such as delirium, aspiration, malnutrition, falls, urinary tract infections (UTI), pressure ulcers, deconditioning, and functional decline. The prevention of these complications requires input from all members of the interdisciplinary team. A postoperative rounding checklist created for the ACS National Surgical Quality Improvement Program (NSQIP)/AGS Best Practices Guideline: Optimal Perioperative Management of the Geriatric Patient provides a template for the evaluations and management strategies that should be performed daily in the geriatric patient to reduce complications postoperatively (Table 7.2). This checklist provides guidance for all of the members of the team.
Table 7.2
Checklist for adverse event prevention/management
Prevention and Management of Delirium
Of all the postoperative complications in the older adults, delirium is the one that is the most challenging and requires the most input for all of the team members to prevent and manage. The prevalence o f postoperative delirium ranges from 9% to 44% depending on the patient population [72]. Thirty to forty percent of postoperative delirium episodes are thought to be preventable [73]. Patients who develop delirium after undergoing elective surgery have been found to have a significantly increased risk of an institutional discharge, prolonged hospitalization, readmission, and death [72].
Factors associated with delirium can be thought of as predisposing (i.e., patient risk factors) and precipitating. The predisposing factors should be determined in the preoperative assessment (see above), and a plan should be in place to mitigate the impact of these risk factors. Precipitating factors include those related to the physiologic insult of surgery, metabolic derangement, infection, inappropriate medications, use of tethers, unfamiliar environment, disturbance of bowel or bladder function, under or over treated pain, or a combination of these factors. When delirium occurs in the postoperative period, it is essential to make a careful search for the precipitating factors and promptly address them.
The initial treatment of delirium is based on removing precipitating factors where possible (i.e., stopping inappropriate medications) and instituting a multicomponent, multidisciplinary nonpharmacological strategy [58], which includes interventions such as:
Early mobility
Beside presence of a family member whenever possible
Cognitive reorientation – the presence of a window and clock in each room
Adaptations for visual and hearing impairment available
Appropriate pain management
Adequate bowel regimen
Removal of tethers such as catheters and lines
Nutrition and fluid repletion
Pharmacologic treatment with antipsychotic medication (i.e., Haldol) and the use of physical restraints should be reserved only for situations where other interventions have failed and the patient is in danger of harming themselves or others. When physical restraints are required, a plan must be in place to provide frequent reassessment of the need and to assist with nutrition, hydration, personal hygiene, and toileting [74].
Delivery of Care Models
As mentioned above, older adults are at increased risk of other serious complications including functional decline and deconditioning, poor nutrition and aspiration, falls, UTI, and pressure ulcers [37, 75]. In this context, input from all of the members of the team is required to provide safe high-quality care. Several models of interdisciplinary care have been developed, tested, and shown to improve care for older adults hospitalized for a variety of conditions, including surgery. For the most part, each model uses the same principles which include multidisciplinary participation, appropriate preoperative evaluation/screening, and standardized geriatric care with interventions based on baseline deficits or those developed during the perioperative period. Clear communication strategies among members of the multidisciplinary team have been identified as an essential component of these models of care [76]. As with any other intervention in healthcare, appropriate implementation of proven practices is critical to obtaining improved results. As such, multidimensional elder care “programs” have been shown to be more effective than any given isolated intervention [37, 76, 77].
The vast majority of data evaluating different acute care models for the geriatric surgical patient originate from studies of older adults undergoing orthopedic procedures, in particular hip fractures. As such the data is limited by both the specific population included (typically frail and vulnerable to other geriatric conditions) and the specific surgical procedure. Nevertheless, the different models provide frameworks through which geriatric surgical care can be improved and optimized in a given clinical surgical practice.
Geriatric Consultation Model
One type of model is based on selective or mandatory geriatric consultation for older adult surgical patients (general surgery, orthopedics, and trauma). Models of this type have been associated with an overall improvement in the process of care including increased geriatric-based assessment and recognition of geriatric syndromes and better advanced care planning [78]. However, a prior non-randomized controlled trial, evaluating the impact of geriatric consults on specific outcomes (length of stay, functional status, mortality, new nursing home admission, and hospital readmission), found no added benefit with the intervention. The authors hypothesized that an independent geriatric consult lacking a more comprehensive program may improve the process of care but not overall patient outcomes [79].
Comanagement Model
A more sophisticated model is one with comanaged perioperative care by surgeons and geriatricians that integrates the multidisciplinary care of the core group and the additional support services (as described above) through a true unified team approach. Although it is difficult to methodologically prove the added benefit of these kinds of models, a systematic review, and other recent studies in the orthopedic literature, has demonstrated improved outcomes (length of stay, mortality, and readmissions) and cost-effectiveness [80–82]. A recent study evaluated the implementation of this model when applied to a number of different surgical specialties and found it to be feasible and associated with overall improved process of care and a trend toward higher rates of regaining independence with increased return to the community upon discharge [83]. The advantages of such a model include the true interdisciplinary care throughout the perioperative continuum and the ability for the different team members to provide added expertise to the day-to-day care.
There are a number of in-patient programs that essentially rely on a comanagement strategy and have proven benefits in different geriatric domains and outcomes after surgery. These programs rely heavily on existing hospital resources, including unit nurses and ancillary staff to implement routine assessment and deliver specific interventions to patients. Such programs include Nurses Improving Care for Health-System Elderly (NICHE – www.nicheprogram.org) and the Hospital Elder Life Program (HELP) [84].
Specialized Units
Lastly, a model that cohorts geriatric patients on a specialized ward or unit has also been advocated by some investigators. There are good data supporting the added benefits of admission to geriatric units in regard to decreased functional decline, 30-day readmissions, and costs, for a general geriatric population [85, 86]. One well-studied example is the Acute Care for Elders (ACE) model [86, 87]. This model provides care for older adults through daily interdisciplinary rounds focusing on geriatric syndromes and through the hardwiring of geriatric care processes into nursing care [86]. It is important to note that “passing on” all the surgical care to the geriatric specialist should not be the goal of care on this kind of unit. The surgical team must continue to provide daily direction and input. Bringing the principles of ACE unit care to all the wards where older adult patients may receive postoperative care is the ideal and is possible if best practices for both medical providers and staff become engrained in the institutional culture [88].
Transition of Care Following the Perioperative Period
As previously discussed, geriatric patients more often require post-acute care prior to returning to their home environment. The transition of care from one phase to another can be a challenging and fragmented process for patients and families [89]. The incidence of readmission following surgery can be up to 20%; many of these represent failures in regaining independence and the ability to return to their baseline state [90]. Additionally, the burden of post-acute care in costs to the patients and the healthcare system is significant. It is among the fastest growing cost in Medicare expenses, representing close to $62 billion annually [4]. There are two well-described models to improve the transition of care, the patient-centered medical home and the transitional care models, both of which have been shown to improve outcomes for older adult patients with multiple comorbidities [91–95]. The patient-centered medical home model works to improve access and coordination of services through a team-based approach achieved through community engagement [93]. The transitional care model centers around an acute hospitalization, where an advanced practice nurse leads a multidisciplinary effort to coordinate the patient’s care from the hospital to the home and has been shown to decrease resource use in cognitively impaired older adults [93]. Patient navigation is a care model with many similarities to the transitional care model, which utilizes trained external coaches or support personnel in a similar fashion, assisting high-risk individuals through the healthcare process and improving their communication with providers and understanding of treatment decisions [96].
As opposed to the young healthy patient who recovers from an uneventful operation, the older adult patient often requires ongoing care even in the absence of complications or geriatric syndromes. The coordination of care during these transitions is essential to prevent readmissions and hasten recovery. The geriatric surgical team must facilitate this process by providing care for any new complications, providing a strategy to prevent functional and cognitive decline, reinitiating presurgical care processes, and communicating effectively with primary care providers. Key components of any given transitional care model include appropriate communication/coordination with the patient’s providers, engagement of family/caregivers, sharing of necessary medical information (medical record), post-discharge follow-up, medication management, education of warning signs specific to each individual patient/procedure, and clarification of ongoing care [6].
Programmatic Efforts to Improve Geriatric Surgical Care
Guidelines for the preoperative assessment and perioperative care of the older adult surgical patient have been developed and disseminated [6, 28], but guidelines alone are not sufficient to bring about a sustained change in practice and improve quality. Over the past several decades, to address a similar problem in other surgical areas, the American College of Surgeons has developed formal quality improvement and verification programs in trauma, cancer, and bariatric surgery, among others. Successful implementation of these programs has been shown to improve quality and outcomes [97, 98]. These successful quality programs are all built on four pillars:
- 1.
Set the standards for what constitutes quality care.
- 2.
Define the infrastructure necessary to provide that care.
- 3.
Collect data on outcomes that can be used to benchmark and continually improve the quality of the care.
- 4.
Verify that the standards, infrastructure, and data collection are in place.
Coalition for Quality in Geriatric Surgery
Using this framework, the ACS and the John A. Hartford Foundation have partnered to develop a formal geriatric surgery quality improvement program, similar to the other ACS quality verification programs. This project, the Coalition for Quality in Geriatric Surgery (CQGS ), brings together 59 national stakeholder organizations, representing surgical, medical and nursing specialists, allied health professionals, social workers, insurers, regulators, and most importantly patients and families to develop a formal program to improve the quality of care for geriatric surgical patients. The coalition will define the standards, processes, resources, and infrastructure necessary to provide high-quality, patient-focused care. Quality geriatric surgical care is built on an interdisciplinary perioperative team that can meet these standards, measure outcomes that matter to the patient, and use the data to continue the cycle of quality improvement. The standards will be based on peer-reviewed evidence and expert consensus opinion. They will include the patient goal-centered consent process, pertinent screening exams, perioperative management strategies, and the team leadership structure that will allow the system to flourish. Meeting the standards consistently requires a multidisciplinary team approach. The infrastructure in place must assure that the standards are met for every patient and are protected from system and human error.
ACS-NSQIP : Geriatric Surgery Pilot
As mentioned above, surgical outcomes usually focus on mortality and morbidity, but older adults are also at risk for functional decline and loss of independence. Factors contributing to these later outcomes, or identifying patients are risk for them, are not routinely measured. To address this gap, the Geriatric Surgery Task Force of the ACS began a Geriatric Surgery Pilot in 2014 to collect geriatric relevant variables in a subset of 23 ACS-NSQIP hospitals across the USA and Canada. Preoperative risk factors and outcomes data were and still are being collected on surgical patients over the age of 65, specifically addressing issues that are important to the geriatric patient (see Table 7.3) [52]. Analysis of this unique data set will allow for the implementation and subsequent measurement of interventions designed to reduce risk and improve outcomes for the geriatric patient population. To learn more about the CQGS program and the Geriatric Surgery Pilot, visit https://www.facs.org/quality-programs/geriatric-coalition.
Table 7.3
Geriatric-specific variables
Preoperative variables | Postoperative variables | 30-day outcomes |
---|---|---|
Origin from home with support | Pressure ulcer | Functional status |
Use of mobility aid | Delirium | Living location |
Fall history | DNR order | |
Dementia history | Palliative care consult | |
Competency on admission | Functional status | |
Palliative care on admission | Fall risk | |
Use of mobility aid | ||
Discharge needs |
Summary
Providing high-quality care for the older adult surgical patients is challenging and requires input from more than just the surgeon and his or her immediate team. It requires a well-coordinated effort by an interdisciplinary team of specialists each of whom always maintains the focus on meeting the patient’s goals of care and preserving the patient’s quality of life. It requires detailed evaluation and planning at every phase, from the decision to do surgery, through the intraoperative and postoperative hospital management, and back to the community. It requires a system-wide awareness of the special issues that older adults face when subjected to the stress of surgery and hospitalization and a programmatic, effective response when predictable issues arise. It requires measurement of outcomes that matter to patients to guide quality improvement efforts. Most of all it requires strong engagement of the whole team with the patient and his or her family to provide a framework where the individual’s vulnerabilities can be anticipated and addressed, in order to provide maximum benefit from the surgery with minimal negative impact on overall function.
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