Introduction .– The prevalence of heart failure and diabetes are both increasing: 25 to 30% of patients with heart failure suffer from diabetes. Diabetics have more diastolic dysfunction because accumulation collagen in intramyocardial.
The objectives of our study are to compare echocardiographics and Doppler profiles of diabetics and non-diabetics.
Patients and methods .– We included 1351 patients, diabetics and non-diabetics, admitted in united of heart failure in our Center of Cardiology from May 2006 to October 2010. All patients were evaluated by echocardiography and Doppler.
The data are presented as numbers, percentages, and medians with interquartile range. The distribution of variables was compared between diabetics and non diabetics by Chi-square test with confidence intervals.
Results .– One thousand three hundred and fifty-one patients were studied, the median age was 63 years. Three hundred and sixty-seven (27%) are diabetics. Overall, it exists similarity of the parameters studied between the 2 groups diabetics and non-diabetics in terms of morphology and hemodynamics (end diastolic left ventricle volume; mitral regurgitation; interventricular septum size; pulmonary arterial systolic pressure; left atrial volume…). But we have found important differences of 3 parameters: ejection fraction of left ventricle was higher (48,5% and 35%) in diabetics group. We found more segmental kinetic disorders (76% and 50%) and more diastolic dysfunction with higher filling pressures (51% and 34%) in diabetic population.
Conclusion .– So, in our study, we have found more diastolic dysfunction and more segmental kinetic disorders but ejection fraction of left ventricle is higher in patients diabetics with chronic heart failure. In general, our results were consistent with most of the European and American studies.
These findings emphasize the importance of individualised management and need for more comprehensive recruitment of diabetics in clinical trials.