A 57-year-old woman with ischaemic stroke was referred to our department for the evaluation of cardiac source of embolism. Transthoracic echocardiography showed a giant mass filling the entire left atrium ( Fig. 1 , Video 1 ). The mass was impeding left ventricular filling by prolapsing into the left ventricular inflow tract in diastole ( Video 2 ). The patient was referred for surgery with presumptive diagnosis of left atrial myxoma. Cardiac catheterization, which was undertaken before surgery, showed normal coronary arteries. Late frames of right ventriculography that coincided with pulmonary venous phase showed a huge filling defect in the left atrium ( Video 3 ). The mass was surrounded by a thin halo of contrast in the remaining left atrium ( Fig. 2 ). The patient was successfully operated on and the pathological diagnosis was myxoma.
