“Underestimation” of a left ventricular threshold




A 75-year-old man with ischaemic left ventricular (LV) dysfunction, left bundle branch block and New York Heart Association class III underwent an uneventful implantation of a cardiac resynchronization therapy (CRT) device. The optimum bipolar LV pacing threshold was obtained in the right ventricular (RV) ring as anode to the LV tip as cathode configuration (1.8 V/0.5 ms during implantation, 1.9 V/0.5 ms before discharge). Two months later, the patient was hospitalized for decompensated heart failure and was considered to be a non-responder to CRT. On device interrogation by a senior cardiologist, the LV threshold was found to be 3 V at 1 ms pulse duration in the bipolar configuration cited above and therefore the LV pacing output was raised without induction of pectoral stimulation. On arrival at the tertiary-care facility, the 12-lead electrocardiogram (ECG) demonstrated a QRS configuration during isolated LV pacing ( Fig. 1 A ) that almost completely resembled that during bipolar RV pacing ( Fig. 1 B). The chest X-ray demonstrated complete dislodgement of the LV lead with its tip lying in the generator pocket. Thus, the previous supposition of an increase in the LV pacing threshold was incorrect as there was no possibility of near-field LV capture with the tip of the lead lying in the generator pocket. What was therefore evident on the 12-lead ECG during LV pacing was an exclusive anodal RV capture. Absence of biventricular pacing also explained the non-response to CRT.


Jul 14, 2017 | Posted by in CARDIOLOGY | Comments Off on “Underestimation” of a left ventricular threshold

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