Cardiovascular effects of acromegaly include which of the following?

1. Left ventricular hypertrophy
   
2. Hypertension
   
3. Insulin resistance and diabetes mellitus
   
4. All of the above

With which of the following is Cushing’s syndrome not associated with?

1. Hypertension
   
2. Diabetes mellitus
   
3. Atrial myxomas
   
4. Mitral regurgitation

What is the triad of hyperpigmentation, low blood pressure, and hyperkalemia suggestive of?

1. Addison’s disease
   
2. Conn’s disease
   
3. Hypopituitarism
   
4. Cushing’s syndrome

Cardiac effects of hyperthyroidism include which of the following?

1. Atrial fibrillation
   
2. High-output heart failure
   
3. Higher blood volume
   
4. All of the above

Which of the following could be cardiac effects of hypothyroidism?

1. Pericardial effusion
   
2. Cardiomyopathy
   
3. Elevated serum cholesterol level
   
4. Low cardiac output and elevated peripheral vascular resistance
   
5. All of the above

Which of the following endocrine disorders may be associated with cardiomyopathy?

1. Hyperthyroidism
   
2. Hypothyroidism
   
3. Pheochromocytoma
   
4. All of the above

Which of the following statements about pheochromocytoma are accurate?

1. About 75% are discovered at autopsy and are commonly missed antemortem
   
2. Most are >1 cm in size and unilateral
   
3. 10% could be familial and in such cases may be multicentric and extra-adrenal
   
4. There is an association with neurofibromatosis
   
5. All of the above

Which of the following statements is not true regarding diagnosis of pheochromocytoma?

1. Plasma catecholamines or 24-h urine metanephrines are good screening tests
   
2. Clonidine suppression test is positive with pheochromocytoma with >50% suppression of serum norepinephrine
   
3. Magnetic resonance imaging (MRI) is the more specific imaging modality compared with computed tomography scan
   
4. Metaiodobenzylguanidine scan is helpful to show that the discovered mass is indeed producing hormones

Deficiency in the enzyme methionine synthase may result in severe hyperhomocysteinemia manifested by which of the following?

1. Premature atherosclerosis
   
2. Venous thrombosis
   
3. Both A and B
   
4. Neither A nor B