Chapter 12 Salvage strategies for severe hypoxemia

Prone positioning

 


• Reverses atelectasis in dependent lung zones
  
   
  
  
• Increases PaO₂
  
   
  
  
• No change in mortality at 28 or 180 days (Ref 3)
  
   
  
  
• More complications, e.g., tube displacement, skin necrosis

Nitric Oxide

 


• Bronchodilator and vasodilator effects when inhaled
  
   
  
  
• Increases PaO₂
  
   
  
  
• Therapeutic range 5 – 20 ppm
  
   
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