A 59-year-old man with a history of extensive anterior myocardial infarction was admitted for progressive shortness of breath attributed to acute decompensation of heart failure. On transthoracic echocardiography there was moderately depressed left ventricular ejection fraction and a large anteroseptal and apical akinesia. The study also showed a large (2 × 2 cm), highly mobile mass attached to the left ventricular apex ( Fig. 1 A and B; Movie 1 ). In this context a thrombus was suspected and intravenous anticoagulation with unfractionated heparin was initiated. Transthoracic real-time three-dimensional echocardiography clearly showed the small pedunculus of the thrombus ( Fig. 1 C ; Movie 2 ). The patient was scheduled for surgery but on echocardiographic control 36 hours later the highly mobile mass had disappeared ( Fig. 1 D). There were no signs or symptoms of systemic embolization. A total body computed tomography scan and arterial Doppler examination of the lower limbs did not disclose arterial occlusion. The patient was discharged on oral anticoagulation and had an uneventful course over the following six months.