Author
Year
Patients
Mean follow-up (months)
Conversion to open
Laparoscopic ligament release
Robotic ligament release
Arterial reconstruction
Immediate clinical improvement
No immediate clinical improvement
Recurrence of symptoms
Mak et al.
2013
46
12
0
46
0
0
31
15
0
Joyce et al.
2013
6
13
0
6
0
0
6
6
0
Do et al.
2013
16
22
0
12
4
0
10
6
0
El Hayek et al.
2013
15
15
1
14
1
0
14
1
0
Bernard et al. [16]
2012
11
35
2
11
0
0
10
1
1
Aschenbach et al. [17]
2011
22
NA
0
22
0
0
22
0
NA
Tulloch [18]
2010
12
14
2
12
0
0
12
0
5
Van Petersen et al. [19]
2009
42
20
1
42
0
0
41
1
NA
Baccari et al. [20]
2009
16
28
2
16
0
3
14
2
0
Roseborough [21]
2009
15
44
4
15
0
0
14
1
1
Vaziri et al. [22]
2008
3
6
0
3
0
0
3
0
0
Totals
204
21
12
204
5
3
177
33
7
Another recent review by Do et al. reported outcomes following laparoscopic MAL release in 16 patients over a 6-year period [10]. Twelve patients were treated with a laparoscopic approach and four patients underwent a robotic-assisted approach. The most common presenting symptom was postprandial abdominal pain. Other symptoms included nausea, vomiting, and weight loss. Five patients had an abdominal bruit on physical examination. The majority of patients laparoscopically treated were women (75 %), and the majority of patients robotically treated were men (75 %). Mean operative times were shorter for the laparoscopic group compared with the robotic-assisted group (101.7 min vs. 145.8 min; p = 0.2). There was no significant difference in hospital length of stay between the two groups. Eight patients (67 %) in the laparoscopic group and two patients (50 %) in the robotic-assisted group had full symptomatic improvement.
Successful outcomes have also been reported following laparoscopic treatment of MALS in the pediatric population. The peer-reviewed literature is currently limited to two series (excluding case reports) reporting outcomes for MALS in children [11, 12]. In a recent review by Mak and colleagues, 46 pediatric patients (mean age 16.2 ± 0.5 years) underwent laparoscopic release of the MAL [11]. In their series, the condition was more common in females (91 %) than males. Patients were screened with preoperative duplex and subsequent CTA if celiac artery compression was present on noninvasive imaging. Overall, 67 % of patients reported improvement of symptoms following their operation. No intraoperative conversions were required and there were no deaths reported in the series.
In another series by Joyce et al., six patients underwent laparoscopic treatment for MALS over a 3-year period [12]. Similar to Mak’s study, the majority of patients were female (83.3 %) with an average age of 15.7 ± 1.5 years. The most common symptoms were postprandial pain (83.3 %) and nausea/vomiting (83.3 %). Other presenting symptoms included epigastric pain (50 %), pain elevated with action (33.3 %), increased bowel activity (16.7 %), and diffuse abdominal pain (16.7 %). Mean operative time and hospital length of stay were 172.5 min and 1.3 days, respectively. Mean peak celiac artery flow (cm/s) was 332.0 preoperatively and decreased to 224.3 postoperatively. A significant improvement from pre- to postsurgical scores was observed in the physical functioning (p = .03), mental health (p = .03), and self-esteem categories (p = .03) of the child assessment. Similarly, there was a significant postsurgical improvement in all categories pertaining to the parent’s quality of life (p = .03). Improvement was also seen in the parents’ perception of their child’s physical functioning (p = .03), bodily pain/discomfort (p = .03), mental health (p = .03), and general health perceptions (p = .03). No intraoperative or postoperative complications occurred. No patient required celiac artery reconstruction and/or revascularization.
Clinical Outcomes of Open Division of the Median Arcuate Ligament
In our review of the published literature, we identified 279 patients between 1963 and 2012 who underwent open MAL division (Table 30.2) [6]. Arterial reconstruction was performed in 72 patients. Of these patients, 223 (80 %) were reported to have immediate symptomatic improvement and late recurrence of symptoms occurred in 22 patients (9.8 %). The incidence of major postoperative complications noted in our review was 6.5 %. Thrombosed arterial bypass grafts were the most complication (2 %). Other complications included stroke (1.4 %), postoperative gastroesophageal reflux disease (1 %), pancreatitis (1 %), hemothorax (0.3 %), and splenic infarction (0.3 %). No procedure-related deaths occurred in any of the papers reviewed for open treatment of MAL.
Table 30.2
Results following open release of the median arcuate ligament
Authors | Year | Patients | Mean follow-up (months) | MAL release | Arterial reconstruction | Immediate clinical improvement | No immediate clinical improvement | Recurrence of symptoms |
---|---|---|---|---|---|---|---|---|
Sultan et al. | 2013 | 11 | 60 | 11 | 3 | 8 | 3 | 0 |
Tulloch et al. | 2010 | 6 | 10 | 6 | 2 | 5 | 1 | 3 |
Grotemeyer et al. | 2009 | 18 | 41
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