Complications, risks, and consequences
Estimatedfrequency
Most significant/serious complications
Infection (overall)
20–50 %
Wound
1–5 %
Urinary
20–50 %
Central nervous system
0.1–1 %
Systemic
1–5 %
Opportunistic (CMVa, candidiasis, pneumocystis)
20–50 %
Gastrointestinal erosion, ulceration, perforation
5–20 %
Abnormal LFTs
5–20 %
Bleeding or hematoma formation
Wound
1–5 %
Perigraft
1–5 %
Paralytic ileus
1–5 %
Significant lymphocele/seroma formation
1–5 %
Ureteric ischemia (causing leak or obstruction)
1–5 %
Vesicoureteric reflux (depends on method of reimplantation)
5–20 %
Thrombosis
Renal artery
0.1–1 %
Renal vein
1–5 %
Renal transplant arterial stenosis – late
1–5 %
Allograft rejection (overall)
20–50 %
Early/late acute (dependant on immunosuppression used)
20–50 %
Chronic
20–50 %
Hyperacute (very rare with current crossmatch techniques)
<0.1 %
Delayed graft function
5–20 %
Immunosuppression toxicity (nephro-/neuro-/myelotoxicity)
20–50 %
Neural injury [e.g., lateral cutaneous nerve of thigh, compressed by retractors]
1–5 %
Malignancy (long term)
20–50 %
Skin malignancy (long term)b
20–50 %
Non-skin malignancy (long term)
5–20 %
Rare significant/serious problems
Cerebral ischemia/hemorrhage/thrombosis (CVA; TIA; RIND)c
0.1–1 %
Deep venous thrombosis/pulmonary embolus
0.1–1 %
Pancreatitis
0.1–1 %
Multisystem organ failurec
0.1–1 %
Death (<30 days)c