Methods
The study included 39 patients (mean age=11.8±3.3; range: 4-19) with chronic mitral regurgitation due to either mitral valve prolapsus (MVP)(27) or rheumatic valve disease(RMR)(12) and 23 healthy children (mean age=10.9±2.81; range: 7-16) as control group. Serum NT-ProBNP levels were obtained, QTc dispersion was calculated using 12-lead ECG; 2D, M-mode, Doppler, Tissue Doppler and Strain echocardiography were performed using Philips IE33 Ecocardiography machine equipped with 5MHz transducer. LV sytolic and diastolic diameters, volumes, ejection fraction, vena contracta, regurgitant volume, effective regurgitant orifis area; global circumferential and longitudinal strain of left ventricle were calculated. The patients were divided into two subgroup as mild or moderate/severe subgroups according to the criteria of European Association of Echocardiography and divided two another subgroups as MVP or rheumatic mitral regurgitation (RMR).
Methods
The study included 39 patients (mean age=11.8±3.3; range: 4-19) with chronic mitral regurgitation due to either mitral valve prolapsus (MVP)(27) or rheumatic valve disease(RMR)(12) and 23 healthy children (mean age=10.9±2.81; range: 7-16) as control group. Serum NT-ProBNP levels were obtained, QTc dispersion was calculated using 12-lead ECG; 2D, M-mode, Doppler, Tissue Doppler and Strain echocardiography were performed using Philips IE33 Ecocardiography machine equipped with 5MHz transducer. LV sytolic and diastolic diameters, volumes, ejection fraction, vena contracta, regurgitant volume, effective regurgitant orifis area; global circumferential and longitudinal strain of left ventricle were calculated. The patients were divided into two subgroup as mild or moderate/severe subgroups according to the criteria of European Association of Echocardiography and divided two another subgroups as MVP or rheumatic mitral regurgitation (RMR).
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