Objective
Bilirubin has important anti-atherosclerotic effects. Prediabetes (PD), the intermediate stage before diabetes mellitus (DM), has increased cardiovascular morbidity and mortality similar to that of DM. We planned to evaluate the relationship between serum bilirubin levels and carotid intima-media thickness (cIMT), as a surrogate marker of subclinical atherosclerosis, in patients with PD.
Methods
We enrolled 170 consecutive patients with PD. The patients underwent ultrasonography to evaluate cIMT. The patients were divided into groups according to cIMT values (<0.9 vs. ≥0.9 mm).